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Literature DB >> 26251649

DREADDnoughts Join in the Battle for Seizure Control.

Matthew J Korn, Jack M Parent.

Abstract

Entities: Disease

Year: 2015 PMID： 26251649 PMCID： PMC4519025 DOI： 10.5698/1535-7597-15.2.85

Source DB: PubMed Journal: Epilepsy Curr ISSN： 1535-7511 Impact factor: 7.500

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8 in total

1. Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.

Authors: Blaine N Armbruster; Xiang Li; Mark H Pausch; Stefan Herlitze; Bryan L Roth
Journal: Proc Natl Acad Sci U S A Date: 2007-03-02 Impact factor: 11.205

Review 2. The RNS System: responsive cortical stimulation for the treatment of refractory partial epilepsy.

Authors: Felice T Sun; Martha J Morrell
Journal: Expert Rev Med Devices Date: 2014-08-21 Impact factor: 3.166

3. Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy.

Authors: Gumei Liu; Bin Gu; Xiao-Ping He; Rasesh B Joshi; Harold D Wackerle; Ramona Marie Rodriguiz; William C Wetsel; James O McNamara
Journal: Neuron Date: 2013-06-20 Impact factor: 17.173

4. Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.

Authors: Karen E Nilsen; Matthew C Walker; Hannah R Cock
Journal: Epilepsia Date: 2005-02 Impact factor: 5.864

5. New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug).

Authors: Vindhya Nawaratne; Katie Leach; Nur Suratman; Richard E Loiacono; Christian C Felder; Blaine N Armbruster; Bryan L Roth; Patrick M Sexton; Arthur Christopoulos
Journal: Mol Pharmacol Date: 2008-07-15 Impact factor: 4.436

DREADDnoughts Join in the Battle for Seizure Control.

1. Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.

Review 2. The RNS System: responsive cortical stimulation for the treatment of refractory partial epilepsy.

3. Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy.

4. Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat.

5. New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug).

Review 6. How might novel technologies such as optogenetics lead to better treatments in epilepsy?

7. Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus→midbrain pathway for feeding behavior.

8. Chemical-genetic attenuation of focal neocortical seizures.