| Literature DB >> 26251140 |
Abstract
Autoimmune hemolytic anemia (AIHA) is a rare paraneoplastic syndrome (PNS) associated with malignant solid tumors. Patients with PNS-AIHA are often refractory to steroid treatment before surgery. The mechanisms underlying PNS-AIHA are not well understood. In a recent case report describing a patient with PNS-AIHA, the antibodies had formed against the tumor antigens and cross-reacted with the erythrocyte antigen: band 3. Further study of this case may provide clues to finding novel mechanisms and targets for immunotherapy against AIHA and solid tumors.Entities:
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Year: 2015 PMID: 26251140 DOI: 10.11406/rinketsu.56.778
Source DB: PubMed Journal: Rinsho Ketsueki ISSN: 0485-1439