| Literature DB >> 26250920 |
Momoko Yoshimoto1, Joyce M Koenig2.
Abstract
Stem cell transplantation (SCT) is an established first-line or adjunctive therapy for a variety of neonatal and adult diseases. New evidence in preclinical models as well as a few human studies show the potential utility of SCT in neuroprotection and in the modulation of inflammatory injury in at risk-neonates. This review briefly summarizes current understanding of human stem cell biology during ontogeny and present recent evidence supporting SCT as a viable approach for postinsult neonatal injury.Entities:
Keywords: Cord blood; Hematopoiesis; Injury; Neonate; Stem cells; Transplantation
Mesh:
Year: 2015 PMID: 26250920 PMCID: PMC4529537 DOI: 10.1016/j.clp.2015.04.008
Source DB: PubMed Journal: Clin Perinatol ISSN: 0095-5108 Impact factor: 3.430