Tin Jasinovic1, Frederick K Kozak2, J Paul Moxham2, Mark Chilvers3, David Wensley3, Michael Seear3, Andrew Campbell4, Jeffrey P Ludemann2. 1. Division of Pediatric Otolaryngology, British Columbia's Children's Hospital, Vancouver, BC, Canada. Electronic address: t.jasinovic@gmail.com. 2. Division of Pediatric Otolaryngology, British Columbia's Children's Hospital, Vancouver, BC, Canada. 3. Division of Pediatric Respirology, British Columbia's Children's Hospital, Vancouver, BC, Canada. 4. Division of Pediatric Cardiac Surgery, British Columbia's Children's Hospital, Vancouver, BC, Canada.
Abstract
OBJECTIVES: To review clinical presentations and management strategies for children with plastic bronchitis. METHODS: Retrospective chart review. RESULTS: Seven patients required rigid bronchoscopy to remove bronchial casts over a 17-year study period. Mean age at presentation was 60 months. Mean follow-up was 53 months. Co-morbidities included: congenital heart disease (n=3), chronic pulmonary disorders (n=2) and sickle cell disease (n=1). 4 patients required multiple bronchoscopies for recurrent casts. Adjunctive topical therapies were administered in all 7 patients, without complication. Rigid bronchoscopy for cast removal was performed in 2 patients who were on extra-corporal membrane oxygenation (ECMO), using special precautions to safeguard the ECMO catheters. CONCLUSIONS: Bronchial casts in children may present acutely or sub-acutely. Recurrent casts are unusual; however, in combination with severe cardiac disease may lead to mortality. Adjunctive topical therapies are still under investigation. Special safeguards for ECMO catheters are imperative. This case series complements and adds to the International Plastic Bronchitis Registry.
OBJECTIVES: To review clinical presentations and management strategies for children with plastic bronchitis. METHODS: Retrospective chart review. RESULTS: Seven patients required rigid bronchoscopy to remove bronchial casts over a 17-year study period. Mean age at presentation was 60 months. Mean follow-up was 53 months. Co-morbidities included: congenital heart disease (n=3), chronic pulmonary disorders (n=2) and sickle cell disease (n=1). 4 patients required multiple bronchoscopies for recurrent casts. Adjunctive topical therapies were administered in all 7 patients, without complication. Rigid bronchoscopy for cast removal was performed in 2 patients who were on extra-corporal membrane oxygenation (ECMO), using special precautions to safeguard the ECMO catheters. CONCLUSIONS: Bronchial casts in children may present acutely or sub-acutely. Recurrent casts are unusual; however, in combination with severe cardiac disease may lead to mortality. Adjunctive topical therapies are still under investigation. Special safeguards for ECMO catheters are imperative. This case series complements and adds to the International Plastic Bronchitis Registry.
Authors: Simon Carter; Dayna van de Hoef; Michael Temple; Elizabeth Harvey; Suhail Al-Saleh; Christoph Licht; Damien Noone Journal: Pediatr Nephrol Date: 2017-06-22 Impact factor: 3.714
Authors: Ilona Pałyga-Bysiecka; Aneta Maria Polewczyk; Maciej Polewczyk; Elżbieta Kołodziej; Henryk Mazurek; Andrzej Pogorzelski Journal: J Clin Med Date: 2021-12-23 Impact factor: 4.241