Literature DB >> 26249701

Structure of GTP-specific succinyl-CoA synthetase in complex with CoA.

Ji Huang1, Manpreet Malhi1, Jan Deneke1, Marie Elizabeth Fraser1.   

Abstract

Pig GTP-specific succinyl-CoA synthetase is an αβ-heterodimer. The crystal structure of the complex with the substrate CoA was determined at 2.1 Å resolution. The structure shows CoA bound to the amino-terminal domain of the α-subunit, with the free thiol extending from the adenine portion into the site where the catalytic histidine residue resides.

Entities:  

Keywords:  ATP-grasp fold; ligase

Mesh：

Substances：

Year:  2015        PMID： 26249701      PMCID： PMC4528943          DOI： 10.1107/S2053230X15011188

Source DB:  PubMed          Journal:  Acta Crystallogr F Struct Biol Commun        ISSN： 2053-230X            Impact factor:   1.056


  23 in total

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Review 2.  Structural classification of proteins: new superfamilies.

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3.  Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase.

Authors:  M E Fraser; M N James; W A Bridger; W T Wolodko
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4.  Probing the nucleotide-binding site of Escherichia coli succinyl-CoA synthetase.

Authors:  M A Joyce; M E Fraser; E R Brownie; M N James; W A Bridger; W T Wolodko
Journal:  Biochemistry       Date:  1999-06-01       Impact factor: 3.162

5.  Deficiency of the ADP-forming succinyl-CoA synthase activity is associated with encephalomyopathy and mitochondrial DNA depletion.

Authors:  Orly Elpeleg; Chaya Miller; Eli Hershkovitz; Maria Bitner-Glindzicz; Gili Bondi-Rubinstein; Shamima Rahman; Alistair Pagnamenta; Sharon Eshhar; Ann Saada
Journal:  Am J Hum Genet       Date:  2005-04-22       Impact factor: 11.025

6.  iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM.

Authors:  T Geoff G Battye; Luke Kontogiannis; Owen Johnson; Harold R Powell; Andrew G W Leslie
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7.  Features and development of Coot.

Authors:  P Emsley; B Lohkamp; W G Scott; K Cowtan
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8.  The crystal structure of succinyl-CoA synthetase from Escherichia coli at 2.5-A resolution.

Authors:  W T Wolodko; M E Fraser; M N James; W A Bridger
Journal:  J Biol Chem       Date:  1994-04-08       Impact factor: 5.157

9.  MolProbity: all-atom structure validation for macromolecular crystallography.

Authors:  Vincent B Chen; W Bryan Arendall; Jeffrey J Headd; Daniel A Keedy; Robert M Immormino; Gary J Kapral; Laura W Murray; Jane S Richardson; David C Richardson
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2009-12-21

10.  Structural basis of CoA recognition by the Pyrococcus single-domain CoA-binding proteins.

Authors:  Takuya B Hiyama; Min Zhao; Yu Kitago; Min Yao; Shun-Ichi Sekine; Takaho Terada; Chizu Kuroishi; Zhi-Jie Liu; John P Rose; Seiki Kuramitsu; Mikako Shirouzu; Nobuhisa Watanabe; Shigeyuki Yokoyama; Isao Tanaka; Bi-Cheng Wang
Journal:  J Struct Funct Genomics       Date:  2007-03-07
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  2 in total

1.  Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.

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Journal:  Proc Natl Acad Sci U S A       Date:  2016-01-19       Impact factor: 11.205

2.  The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase.

Authors:  Ji Huang; Marie E Fraser
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2022-09-26       Impact factor: 1.072
  2 in total

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