| Literature DB >> 26249603 |
R Emmanuel1, Selvakumar Palanisamy2, Shen-Ming Chen3, K Chelladurai2, S Padmavathy4, M Saravanan5, P Prakash6, M Ajmal Ali7, Fahad M A Al-Hemaid7.
Abstract
Development of biologically inspired green synthesis of silver nanoparticles is evolving into an important branch of nano-biotechnology. In the present investigation, we report the green synthesis of silver nanoparticles (AgNPs) employing the leaf extract of Justicia glauca. Water-soluble organics present in the leaf extract are mainly responsible for the reduction of silver nitrate (AgNO3) solution to AgNPs. The AgNPs are 10-20nm in dimensions as determined by TEM images. The antimicrobial activities of green synthesized AgNPs and drug blended AgNPs have been evaluated against the dental caries and periodontal disease causing microorganisms such as Streptococcus mutans, Staphylococcus aureus, Lactobacillus acidophilus, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. The AgNPs and drug blended AgNPs show a significant antibacterial and antifungal activity. Minimum inhibitory concentration (MIC) value of AgNPs determined against the selected dental caries and periodontal disease causing microorganisms are noticeable between the range of 25-75μg/mL.Entities:
Keywords: Antimicrobial activities; Dental caries; Justicia glauca; Periodontal disease; Silver nanoparticles
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Year: 2015 PMID： 26249603 DOI： 10.1016/j.msec.2015.06.033
Source DB: PubMed Journal: Mater Sci Eng C Mater Biol Appl ISSN： 0928-4931 Impact factor: 7.328