Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A luminescent ruthenium(II) complex for light-triggered drug release and live cell imaging.

Literature DB >> 26248575

A luminescent ruthenium(II) complex for light-triggered drug release and live cell imaging.

Abstract

We report a novel ruthenium(II) complex for selective release of the imidazole-based drug econazole. While the complex is highly stable and luminescent in the dark, irradiation with green light induces release of one of the econazole ligands, which is accompanied by a turn-off luminescence response and up to a 34-fold increase in cytotoxicity towards tumour cells.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2015 PMID： 26248575 DOI： 10.1039/c5cc05172j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

Keyword Cloud
Cited

23 in total

1. Effects of Methyl Substitution in Ruthenium Tris(2-pyridylmethyl)amine Photocaging Groups for Nitriles.

Authors: Karan Arora; Jessica K White; Rajgopal Sharma; Shivnath Mazumder; Philip D Martin; H Bernhard Schlegel; Claudia Turro; Jeremy J Kodanko
Journal: Inorg Chem Date: 2016-06-29 Impact factor: 5.165

2. Photoactivation of imatinib-antibody conjugate using low-energy visible light from Ru(ii)-polypyridyl cages.

Authors: Thomas N Rohrabaugh; Ashley M Rohrabaugh; Jeremy J Kodanko; Jessica K White; Claudia Turro
Journal: Chem Commun (Camb) Date: 2018-05-17 Impact factor: 6.222

3. Copper potentiates azole antifungal activity in a way that does not involve complex formation.

Authors: Elizabeth W Hunsaker; Katherine J Franz
Journal: Dalton Trans Date: 2019-07-02 Impact factor: 4.390

4. Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Authors: Roy Weinstain; Tomáš Slanina; Dnyaneshwar Kand; Petr Klán
Journal: Chem Rev Date: 2020-10-30 Impact factor: 60.622

5. Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands.

Authors: Lars Kohler; Leona Nease; Pascal Vo; Jenna Garofolo; David K Heidary; Randolph P Thummel; Edith C Glazer
Journal: Inorg Chem Date: 2017-09-26 Impact factor: 5.165

A luminescent ruthenium(II) complex for light-triggered drug release and live cell imaging.

1. Effects of Methyl Substitution in Ruthenium Tris(2-pyridylmethyl)amine Photocaging Groups for Nitriles.

2. Photoactivation of imatinib-antibody conjugate using low-energy visible light from Ru(ii)-polypyridyl cages.

3. Copper potentiates azole antifungal activity in a way that does not involve complex formation.

4. Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

5. Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands.

6. Ru(ii) polypyridyl complexes as photocages for bioactive compounds containing nitriles and aromatic heterocycles.

7. DFT Investigation of Ligand Photodissociation in [Ru^II(tpy)(bpy)(py)]²⁺ and [Ru^II(tpy)(Me₂bpy)(py)]²⁺ Complexes.

8. Ru(II) Polypyridyl Complexes Derived from Tetradentate Ancillary Ligands for Effective Photocaging.

Review 9. The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

10. Selective Release of Aromatic Heterocycles from Ruthenium Tris(2-pyridylmethyl)amine with Visible Light.