Literature DB >> 26246165

Neuroprotective therapies: Preclinical reproducibility is only part of the problem.

Michael Tymianski1.   

Abstract

Among the many unknowns in the translational path to developing drugs for acute stroke, addressing the reproducibility of preclinical data is only one piece of a multifaceted and incomplete puzzle (Llovera et al., this issue).
Copyright © 2015, American Association for the Advancement of Science.

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Year:  2015        PMID： 26246165     DOI： 10.1126/scitranslmed.aac9412

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  7 in total

1.  Inadequate food and water intake determine mortality following stroke in mice.

Authors:  Athanasios Lourbopoulos; Uta Mamrak; Stefan Roth; Matilde Balbi; Joshua Shrouder; Arthur Liesz; Farida Hellal; Nikolaus Plesnila
Journal:  J Cereb Blood Flow Metab       Date:  2016-01-01       Impact factor: 6.200

2.  Early Neurological Change After Ischemic Stroke Is Associated With 90-Day Outcome.

Authors:  Laura Heitsch; Laura Ibanez; Caty Carrera; Michael M Binkley; Daniel Strbian; Turgut Tatlisumak; Alejandro Bustamante; Marc Ribó; Carlos Molina; Antoni Dávalos; Elena López-Cancio; Lucia Muñoz-Narbona; Carol Soriano-Tárraga; Eva Giralt-Steinhauer; Victor Obach; Agnieszka Slowik; Joanna Pera; Katarzyna Lapicka-Bodzioch; Justyna Derbisz; Tomás Sobrino; José Castillo; Francisco Campos; Emilio Rodríguez-Castro; Susana Arias-Rivas; Tomas Segura; Gemma Serrano-Heras; Cristófol Vives-Bauza; Rosa Díaz-Navarro; Silva Tur; Carmen Jimenez; Joan Martí-Fàbregas; Raquel Delgado-Mederos; Juan Arenillas; Jerzy Krupinski; Natalia Cullell; Nuria P Torres-Aguila; Elena Muiño; Jara Cárcel-Márquez; Francisco Moniche; Juan A Cabezas; Andria L Ford; Rajat Dhar; Jaume Roquer; Pooja Khatri; Jordi Jiménez-Conde; Israel Fernandez-Cadenas; Joan Montaner; Jonathan Rosand; Carlos Cruchaga; Jin-Moo Lee
Journal:  Stroke       Date:  2020-12-15       Impact factor: 7.914

3.  Hyperoxia results in increased aerobic metabolism following acute brain injury.

Authors:  Arnab Ghosh; David Highton; Christina Kolyva; Ilias Tachtsidis; Clare E Elwell; Martin Smith
Journal:  J Cereb Blood Flow Metab       Date:  2016-01-01       Impact factor: 6.200

Review 4.  Managing risks in drug discovery: reproducibility of published findings.

Authors:  Aimo Kannt; Thomas Wieland
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-02-17       Impact factor: 3.000

Review 5.  C-Phycocyanin and Phycocyanobilin as Remyelination Therapies for Enhancing Recovery in Multiple Sclerosis and Ischemic Stroke: A Preclinical Perspective.

Authors:  Giselle Pentón-Rol; Javier Marín-Prida; Viviana Falcón-Cama
Journal:  Behav Sci (Basel)       Date:  2018-01-18

6.  Predicting experimental success: a retrospective case-control study using the rat intraluminal thread model of stroke.

Authors:  Lisa Liebenstund; Mark Coburn; Christina Fitzner; Antje Willuweit; Karl-Josef Langen; Jingjin Liu; Michael Veldeman; Anke Höllig
Journal:  Dis Model Mech       Date:  2020-12-29       Impact factor: 5.758

7.  Multicentre translational Trial of Remote Ischaemic Conditioning in Acute Ischaemic Stroke (TRICS): protocol of multicentre, parallel group, randomised, preclinical trial in female and male rat and mouse from the Italian Stroke Organization (ISO) Basic Science network.

Authors:  Mauro Tettamanti; Simone Beretta; Giuseppe Pignataro; Stefano Fumagalli; Carlo Perego; Luigi Sironi; Felicita Pedata; Diana Amantea; Marco Bacigaluppi; Antonio Vinciguerra; Alessia Valente; Susanna Diamanti; Jacopo Mariani; Martina Viganò; Francesco Santangelo; Chiara Paola Zoia; Virginia Rogriguez-Menendez; Laura Castiglioni; Joanna Rzemieniec; Ilaria Dettori; Irene Bulli; Elisabetta Coppi; Giorgia Serena Gullotta; Giacinto Bagetta; Gianvito Martino; Carlo Ferrarese; Maria Grazia De Simoni
Journal:  BMJ Open Sci       Date:  2020-11-24
  7 in total

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