Sriram Krishnamurthy1, Kuralvanan Gunasekaran, Subramanian Mahadevan, Zachariah Bobby, Ajith Prabhu Kumar. 1. Departments of Pediatrics, *Biochemistry and #Community Medicine; Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India. Correspondence to: Dr. Subramanian Mahadevan, Professor, Department of Pediatrics, JIPMER, Puducherry 605 006, India. mahadevan.subramanian80@gmail.com.
Abstract
OBJECTIVE: To determine the frequency and risk factors of acute kidney injury in children with Russells viper envenomation using Acute Kidney Injury Network definition and classification system. METHODS: A prospective observational study recruiting 61 subjects managed as per the National Snakebite Protocol. RESULTS: 45.9% of envenomed children had acute kidney injury. The median (IQR) of the maximum serum creatinine level during hospitalization was 2 (1.3-4.8) mg/dL. The distribution of stages 1, 2 and 3 of acute kidney injury was 32.1%, 17.9% and 50% respectively. Dialysis was required in 35.7% of the children with acute kidney injury. CONCLUSION: Acute kidney injury is common with Russells viper envenomation. Native treatments and bleeding manifestations were associated with acute kidney injury in our patient population.
OBJECTIVE: To determine the frequency and risk factors of acute kidney injury in children with Russells viper envenomation using Acute Kidney Injury Network definition and classification system. METHODS: A prospective observational study recruiting 61 subjects managed as per the National Snakebite Protocol. RESULTS: 45.9% of envenomed children had acute kidney injury. The median (IQR) of the maximum serum creatinine level during hospitalization was 2 (1.3-4.8) mg/dL. The distribution of stages 1, 2 and 3 of acute kidney injury was 32.1%, 17.9% and 50% respectively. Dialysis was required in 35.7% of the children with acute kidney injury. CONCLUSION:Acute kidney injury is common with Russells viper envenomation. Native treatments and bleeding manifestations were associated with acute kidney injury in our patient population.