Literature DB >> 26240093

Brown tumours of the tibia and second metacarpal bone in a woman with severe vitamin D deficiency.

Butheinah A Al-Sharafi1, Shafiq A Al-Imad2, Amani M Shamshair3, Derhim H Al-Faqeeh4.   

Abstract

Brown tumours caused by vitamin D deficiency are rare. Most cases are caused by primary hyperparathyroidism, and are rarely caused by secondary hyperparathyroidism in cases of renal failure. We present a case of Brown tumours of the tibia and second metacarpal bone in a 50-year-old woman who had a low dietary intake of vitamin D and had worn a veil for most of her adult life. The Brown tumours were caused by vitamin D deficiency and secondary hyperparathyroidism. The patient improved on treatment with vitamin D3 and calcium supplements. This is a rare case and the first, to our knowledge, with a Brown tumour of the tibia caused by vitamin D deficiency due to decreased dietary intake and decreased exposure to sunlight. The course of treatment and investigations of the patient are described. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26240093      PMCID: PMC4533646          DOI: 10.1136/bcr-2014-207722

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  17 in total

1.  Simultaneously occurring brown tumours in the mandible and maxilla in a patient with vitamin D deficiency.

Authors:  C Pace; R Crosher
Journal:  Aust Dent J       Date:  2010-12       Impact factor: 2.291

2.  A brown tumor after biliopancreatic diversion for severe obesity.

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Journal:  Endocr J       Date:  2008-12-27       Impact factor: 2.349

3.  Central giant cell granuloma: a case report.

Authors:  Ravi Prakash Sasankoti Mohan; Sankalp Verma; Neha Agarwal; Udita Singh
Journal:  BMJ Case Rep       Date:  2013-07-22

4.  Regression of a brown tumour after 3 years of treatment with intravenous calcitriol in a haemodialysis patient.

Authors:  E Fernández; M Balart; J Montoliu
Journal:  Nephrol Dial Transplant       Date:  1996-02       Impact factor: 5.992

5.  A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial.

Authors:  P Lips; T Duong; A Oleksik; D Black; S Cummings; D Cox; T Nickelsen
Journal:  J Clin Endocrinol Metab       Date:  2001-03       Impact factor: 5.958

6.  Secondary hyperparathyroidism and brown tumor in dialyzed patients.

Authors:  B Jeren-Strujić; B Rozman; S Lambasa; T Jeren; M Marković; V Raos
Journal:  Ren Fail       Date:  2001-03       Impact factor: 2.606

7.  Secondary hyperparathyroidism and brown tumors in a patient with gluten enteropathy.

Authors:  G W Ehrlich; H K Genant; F O Kolb
Journal:  AJR Am J Roentgenol       Date:  1983-08       Impact factor: 3.959

Review 8.  Vitamin D and bone health: Epidemiologic studies.

Authors:  Peter R Ebeling
Journal:  Bonekey Rep       Date:  2014-03-05

9.  Low 25-hydroxyvitamin D and normal serum calcium concentrations in Saudi Arabia: Riyadh region.

Authors:  S H Sedrani
Journal:  Ann Nutr Metab       Date:  1984       Impact factor: 3.374

10.  Brown tumor in mandible as a first sign of vitamin D deficiency: A rare case report and review.

Authors:  K V Arunkumar; Sanjeev Kumar; D Deepa
Journal:  Indian J Endocrinol Metab       Date:  2012-03
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  1 in total

1.  A Brown Tumor of Tibial Diaphysis Masquerading as Malignancy.

Authors:  Raju Vaishya; Amit Kumar Agarwal; Vipul Vijay; Abhishek Vaish
Journal:  Cureus       Date:  2017-06-06
  1 in total

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