Literature DB >> 26239769

Association between GABA(A) receptor subunit polymorphisms and autism spectrum disorder (ASD).

Carla V Sesarini1, Lucas Costa2, Nora Grañana3, Miguel Garcia Coto4, Roberto C Pallia5, Pablo F Argibay2.   

Abstract

ASD might be associated with alterations in excitation/inhibition ratio and GABA(A) has been implicated since it mediates synaptic inhibition. Polymorphisms in GABA receptor (GABAR) were studied: significant differences in allele and genotype frequencies observed between cases and controls (rs1912960, GABRA4). Haplotype analysis: rs1912960 (GABRA4) and rs211037 (GABRG2) overrepresented in cases. Rs1912960 has been associated with ASD and rs211037 with epilepsy. GABRA4 is associated with autism in the Argentinean dataset independently or in combination with GABRG2.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Allelic and genotypic association; Argentinean sample; Epilepsy

Mesh：

Substances：

Year:  2015        PMID： 26239769     DOI： 10.1016/j.psychres.2015.07.077

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  9 in total

1.  Chronic sodium bromide treatment relieves autistic-like behavioral deficits in three mouse models of autism.

Authors:  Julie Le Merrer; Jerome A J Becker; Cécile Derieux; Audrey Léauté; Agathe Brugoux; Déborah Jaccaz; Claire Terrier; Jean-Philippe Pin; Julie Kniazeff
Journal:  Neuropsychopharmacology       Date:  2022-04-13       Impact factor: 8.294

Review 2.  Meta-Analysis of the Association between GABA Receptor Polymorphisms and Autism Spectrum Disorder (ASD).

Authors:  Manijeh Mahdavi; Majid Kheirollahi; Roya Riahi; Fariborz Khorvash; Mehdi Khorrami; Maryam Mirsafaie
Journal:  J Mol Neurosci       Date:  2018-05-03       Impact factor: 3.444

3.  The Neurobiological Basis for Social Affiliation in Autism Spectrum Disorder and Schizophrenia.

Authors:  Amanda Crider; Anilkumar Pillai
Journal:  Curr Behav Neurosci Rep       Date:  2016-04-16

4.  Meta-analysis of GABRB3 Gene Polymorphisms and Susceptibility to Autism Spectrum Disorder.

Authors:  Rezvan Noroozi; Mohammad Taheri; Soudeh Ghafouri-Fard; Zeinab Bidel; Mir Davood Omrani; Ali Sanjari Moghaddam; Parisa Sarabi; Alireza Mosavi Jarahi
Journal:  J Mol Neurosci       Date:  2018-07-18       Impact factor: 3.444

5.  Interactive effects of OXTR and GAD1 on envy-associated behaviors and neural responses.

Authors:  Toshiko Tanaka; Fumichika Nishimura; Chihiro Kakiuchi; Kiyoto Kasai; Minoru Kimura; Masahiko Haruno
Journal:  PLoS One       Date:  2019-01-11       Impact factor: 3.240

6.  Mechanisms underlying the EEG biomarker in Dup15q syndrome.

Authors:  Joerg F Hipp; Shafali S Jeste; Joel Frohlich; Lawrence T Reiter; Vidya Saravanapandian; Charlotte DiStefano; Scott Huberty; Carly Hyde; Stormy Chamberlain; Carrie E Bearden; Peyman Golshani; Andrei Irimia; Richard W Olsen
Journal:  Mol Autism       Date:  2019-07-03       Impact factor: 7.509

7.  A systematic review of common genetic variation and biological pathways in autism spectrum disorder.

Authors:  Diego Alejandro Rodriguez-Gomez; Danna Paola Garcia-Guaqueta; Jesús David Charry-Sánchez; Elias Sarquis-Buitrago; Mariana Blanco; Alberto Velez-van-Meerbeke; Claudia Talero-Gutiérrez
Journal:  BMC Neurosci       Date:  2021-10-09       Impact factor: 3.288

Review 8.  Common Ribs of Inhibitory Synaptic Dysfunction in the Umbrella of Neurodevelopmental Disorders.

Authors:  Rachel Ali Rodriguez; Christina Joya; Rochelle M Hines
Journal:  Front Mol Neurosci       Date:  2018-04-24       Impact factor: 5.639

9.  An Investigation of SDF1/CXCR4 Gene Polymorphisms in Autism Spectrum Disorder: A Family-Based Study.

Authors:  Tayfun Kara; İsmail Akaltun; Bedia Cakmakoglu; İlyas Kaya; Salih Zoroğlu
Journal:  Psychiatry Investig       Date:  2018-02-22       Impact factor: 2.505
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.