Literature DB >> 26238676

Combating Superbug Without Antibiotic on a Postamputation Wound in a Patient with Diabetic Foot.

Shuyao Sun1, Chun Wang1, Dawei Chen1, Shiqiang Cen1, Xiaoju Lv1, Xiaorong Wen1, Min Liu1, Wusheng Lu1, Jichun Zhao1, Xingwu Ran2.   

Abstract

Diabetic foot is a kind of limb- and life-threatening complication that is difficult to treat with conventional therapy, especially when accompanied with peripheral arterial insufficiency and severe infection. We present a diabetic patient with a postamputation wound infected by multidrug-resistant Acinetobacter baumannii/haemolyticus, which was resistant to almost all antibiotics. As the clinical response to antimicrobial therapy was poor, antibiotic was discontinued. Autologous platelet-rich gel with anticoagulation, negative pressure wound therapy, and improvement of microcirculation were used successfully to eradicate infection of the superbug and achieve final wound closure.
© The Author(s) 2015.

Entities:  

Keywords:  autologous platelet-rich gel; diabetic foot; multidrug-resistant bacterial infection; negative pressure wound therapy

Mesh:

Substances:

Year:  2015        PMID: 26238676     DOI: 10.1177/1534734615595736

Source DB:  PubMed          Journal:  Int J Low Extrem Wounds        ISSN: 1534-7346            Impact factor:   2.057


  4 in total

1.  The efficacy of platelet-rich plasma gel in MRSA-related surgical wound infection treatment: an experimental study in an animal model.

Authors:  R A Cetinkaya; S Yilmaz; A Ünlü; P Petrone; C Marini; E Karabulut; M Urkan; E Kaya; K Karabacak; M Uyanik; I Eker; A Kilic; A Gunal
Journal:  Eur J Trauma Emerg Surg       Date:  2017-09-30       Impact factor: 3.693

Review 2.  Microbial Infection and Antibiotic Susceptibility of Diabetic Foot Ulcer in China: Literature Review.

Authors:  Fang Du; Jing Ma; Hongping Gong; Raju Bista; Panpan Zha; Yan Ren; Yun Gao; Dawei Chen; Xingwu Ran; Chun Wang
Journal:  Front Endocrinol (Lausanne)       Date:  2022-05-19       Impact factor: 6.055

3.  Comparison of Allogeneic Platelet-rich Plasma With Autologous Platelet-rich Plasma for the Treatment of Diabetic Lower Extremity Ulcers.

Authors:  Min He; Xuewen Guo; Tao Li; Xiaoyan Jiang; Yan Chen; Yi Yuan; Bing Chen; Gangyi Yang; Yahan Fan; Ziwen Liang; David G Armstrong; Wuquan Deng
Journal:  Cell Transplant       Date:  2020 Jan-Dec       Impact factor: 4.064

4.  Healing of Chronic Wounds with Platelet-Derived Growth Factors from Single Donor Platelet-Rich Plasma following One Freeze-Thaw Cycle. A Cross-Sectional Study.

Authors:  Julia Vidán-Estévez; Sergio Sánchez-Herráez; Fernando Escalante-Barrigón; Jesús Seco-Calvo
Journal:  J Clin Med       Date:  2021-12-09       Impact factor: 4.241

  4 in total

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