Jenny Theorell-Haglöw1, Torbjörn Åkerstedt2, Johanna Schwarz2,3, Eva Lindberg1. 1. Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden. 2. Stress Research Institute, Stockholm University, Sweden. 3. Department of Psychology, Stockholm University, Sweden.
Abstract
STUDY OBJECTIVES: To analyze predictors of excessive daytime sleepiness (EDS) and to analyze how changes within risk factors over time predict incident EDS in women. DESIGN: Population-based prospective study. SETTING: General population of the City of Uppsala, Sweden. PARTICIPANTS: From a random, general population sample of 7,051 women from the Sleep and HEalth in women ("SHE") cohort, 4,322 women without EDS at baseline were followed up after 10 y. INTERVENTIONS: N/A. MEASUREMENTS AND RESULTS: At baseline and follow-up, women answered a questionnaire on sleeping habits, somatic disease, obesity, insomnia, anxiety and depression, lifestyle, and social factors. The risk of incident EDS was analyzed from changes over time in risk factors using logistic regression modeling. Of the women, EDS developed in 7.9%. Incident: insomnia (adjusted odds ratio = 5.01; 95% confidence interval 3.63-6.92), anxiety and/or depression (3.34; 2.22-5.02), somatic disease (1.73; 1.17-2.55), obesity (1.91; 1.14-2.57), snoring (1.91; 1.17-3.10) and smoking (4.31; 1.95-9.54) were all independent risk factors for the development of EDS. In addition, persistent: insomnia (4.44; 2.97-6.65) and anxiety and/or depression (4.91; 3.17-7.62) increased the risk of developing EDS. Apart from incident: snoring and obesity, similar results were obtained when only including women without somatic disease in the analyses. CONCLUSION: Insomnia, anxiety and/or depression, and smoking were the most important factors for predicting incident excessive daytime sleepiness (EDS) and, in addition, somatic disease, obesity, and snoring predicted EDS. It is important not only to treat these conditions but also to inform women of the importance of a healthy lifestyle in order to prevent and reduce EDS in women.
STUDY OBJECTIVES: To analyze predictors of excessive daytime sleepiness (EDS) and to analyze how changes within risk factors over time predict incident EDS in women. DESIGN: Population-based prospective study. SETTING: General population of the City of Uppsala, Sweden. PARTICIPANTS: From a random, general population sample of 7,051 women from the Sleep and HEalth in women ("SHE") cohort, 4,322 women without EDS at baseline were followed up after 10 y. INTERVENTIONS: N/A. MEASUREMENTS AND RESULTS: At baseline and follow-up, women answered a questionnaire on sleeping habits, somatic disease, obesity, insomnia, anxiety and depression, lifestyle, and social factors. The risk of incident EDS was analyzed from changes over time in risk factors using logistic regression modeling. Of the women, EDS developed in 7.9%. Incident: insomnia (adjusted odds ratio = 5.01; 95% confidence interval 3.63-6.92), anxiety and/or depression (3.34; 2.22-5.02), somatic disease (1.73; 1.17-2.55), obesity (1.91; 1.14-2.57), snoring (1.91; 1.17-3.10) and smoking (4.31; 1.95-9.54) were all independent risk factors for the development of EDS. In addition, persistent: insomnia (4.44; 2.97-6.65) and anxiety and/or depression (4.91; 3.17-7.62) increased the risk of developing EDS. Apart from incident: snoring and obesity, similar results were obtained when only including women without somatic disease in the analyses. CONCLUSION:Insomnia, anxiety and/or depression, and smoking were the most important factors for predicting incident excessive daytime sleepiness (EDS) and, in addition, somatic disease, obesity, and snoring predicted EDS. It is important not only to treat these conditions but also to inform women of the importance of a healthy lifestyle in order to prevent and reduce EDS in women.
Authors: Joseph P H McNamara; Jiantong Wang; David B Holiday; Jessica Young Warren; Marilyn Paradoa; Amanda Marie Balkhi; Jeannette Fernandez-Baca; Christina S McCrae Journal: Psychol Health Med Date: 2013-09-17 Impact factor: 2.423
Authors: Julio Fernandez-Mendoza; Alexandros N Vgontzas; Ilia Kritikou; Susan L Calhoun; Duanping Liao; Edward O Bixler Journal: Sleep Date: 2015-03-01 Impact factor: 5.849
Authors: John B Dixon; Maureen E Dixon; Margaret L Anderson; Linda Schachter; Paul E O'brien Journal: Obesity (Silver Spring) Date: 2007-10 Impact factor: 5.002
Authors: Ina van der Spuy; Chandima P Karunanayake; James A Dosman; Kathleen McMullin; Gaungming Zhao; Sylvia Abonyi; Donna C Rennie; Joshua Lawson; Shelley Kirychuk; Judith MacDonald; Laurie Jimmy; Niels Koehncke; Vivian R Ramsden; Mark Fenton; Gregory P Marchildon; Malcolm King; Punam Pahwa Journal: BMC Pulm Med Date: 2017-12-12 Impact factor: 3.317