Literature DB >> 26237090

Wobble↔Watson-Crick tautomeric transitions in the homo-purine DNA mismatches: a key to the intimate mechanisms of the spontaneous transversions.

Ol'ha O Brovarets'1,2, Dmytro M Hovorun1,2.   

Abstract

The intrinsic capability of the homo-purine DNA base mispairs to perform wobble↔Watson-Crick/Topal-Fresco tautomeric transitions via the sequential intrapair double proton transfer was discovered for the first time using QM (MP2/DFT) and QTAIM methodologies that are crucial for understanding the microstructural mechanisms of the spontaneous transversions.

Entities:  

Keywords:  DNA biosynthesis; MP2 and B3LYP; QTAIM; Watson–Crick-like mispair; homo-purine mismatch; incorporation error; spontaneous transversion; tautomeric transition

Mesh：

Substances：

Year:  2015        PMID： 26237090     DOI： 10.1080/07391102.2015.1077737

Source DB:  PubMed          Journal:  J Biomol Struct Dyn        ISSN： 0739-1102


  11 in total

1.  Structure and Dynamics of DNA and RNA Double Helices of CAG and GAC Trinucleotide Repeats.

Authors:  Feng Pan; Viet Hoang Man; Christopher Roland; Celeste Sagui
Journal:  Biophys J       Date:  2017-07-11       Impact factor: 4.033

2.  The A·T(rWC)/A·T(H)/A·T(rH) ↔ A·T*(rwWC)/A·T*(wH)/A·T*(rwH) mutagenic tautomerization via sequential proton transfer: a QM/QTAIM study.

Authors:  Ol'ha O Brovarets'; Kostiantyn S Tsiupa; Dmytro M Hovorun
Journal:  RSC Adv       Date:  2018-04-10       Impact factor: 4.036

3.  Effects of Environmental Factors and Metallic Electrodes on AC Electrical Conduction Through DNA Molecule.

Authors:  S Abdalla; A Obaid; F M Al-Marzouki
Journal:  Nanoscale Res Lett       Date:  2017-04-27       Impact factor: 4.703

4.  Surprising Conformers of the Biologically Important A·T DNA Base Pairs: QM/QTAIM Proofs.

Authors:  Ol'ha O Brovarets'; Kostiantyn S Tsiupa; Dmytro M Hovorun
Journal:  Front Chem       Date:  2018-02-27       Impact factor: 5.221

5.  Novel pathway for mutagenic tautomerization of classical А∙Т DNA base pairs via sequential proton transfer through quasi-orthogonal transition states: A QM/QTAIM investigation.

Authors:  Ol'ha O Brovarets'; Kostiantyn S Tsiupa; Dmytro M Hovorun
Journal:  PLoS One       Date:  2018-06-27       Impact factor: 3.240

6.  Unexpected Routes of the Mutagenic Tautomerization of the T Nucleobase in the Classical A·T DNA Base Pairs: A QM/QTAIM Comprehensive View.

Authors:  Ol'ha O Brovarets'; Kostiantyn S Tsiupa; Andrii Dinets; Dmytro M Hovorun
Journal:  Front Chem       Date:  2018-11-27       Impact factor: 5.221

7.  A Quantum-Mechanical Looking Behind the Scene of the Classic G·C Nucleobase Pairs Tautomerization.

Authors:  Ol'ha O Brovarets'; Alona Muradova; Dmytro M Hovorun
Journal:  Front Chem       Date:  2020-11-26       Impact factor: 5.221

8.  Non-dissociative structural transitions of the Watson-Crick and reverse Watson-Crick А·Т DNA base pairs into the Hoogsteen and reverse Hoogsteen forms.

Authors:  Ol'ha O Brovarets'; Kostiantyn S Tsiupa; Dmytro M Hovorun
Journal:  Sci Rep       Date:  2018-07-10       Impact factor: 4.379

Review 9.  The Role of Proton Transfer on Mutations.

Authors:  Ruby Srivastava
Journal:  Front Chem       Date:  2019-08-21       Impact factor: 5.221

10.  Novel Tautomerisation Mechanisms of the Biologically Important Conformers of the Reverse Löwdin, Hoogsteen, and Reverse Hoogsteen G*·C* DNA Base Pairs via Proton Transfer: A Quantum-Mechanical Survey.

Authors:  Ol'ha O Brovarets'; Timothy A Oliynyk; Dmytro M Hovorun
Journal:  Front Chem       Date:  2019-09-18       Impact factor: 5.221
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