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Literature DB >> 26236652

Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery Systems: Recent Breakthroughs.

Jafar Ezzati Nazhad Dolatabadi¹, Hadi Valizadeh², Hamed Hamishehkar³.

Abstract

In recent years, nanomaterials have been widely applied as advanced drug and gene delivery nanosystems. Among them, solid lipid nanoparticles (SLNs) have attracted great attention as colloidal drug delivery systems for incorporating hydrophilic or lipophilic drugs and various macromolecules as well as proteins and nucleic acids. Therefore, SLNs offer great promise for controlled and site specific drug and gene delivery. This article includes general information about SLN structures and properties, production procedures, characterization. In addition, recent progress on development of drug and gene delivery systems using SLNs was reviewed.

Entities: Chemical

Keywords: Drug delivery; Gene delivery; Solid lipid nanoparticles; colloidal carrier

Year: 2015 PMID： 26236652 PMCID： PMC4517084 DOI： 10.15171/apb.2015.022

Source DB: PubMed Journal: Adv Pharm Bull ISSN： 2228-5881

63 in total

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Journal: Eur J Pharm Sci Date: 2012-11-12 Impact factor: 4.384

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Journal: Chem Phys Lipids Date: 2014-04-06 Impact factor: 3.329

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Journal: Eur J Pharm Biopharm Date: 2013-09-02 Impact factor: 5.571

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Journal: Indian J Pharm Sci Date: 2009-07 Impact factor: 0.975

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Authors: Phong A Tran; Lijie Zhang; Thomas J Webster
Journal: Adv Drug Deliv Rev Date: 2009-08-06 Impact factor: 15.470

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Authors: A C Silva; A Kumar; W Wild; D Ferreira; D Santos; B Forbes
Journal: Int J Pharm Date: 2012-08-04 Impact factor: 5.875

10. Development of dry powder inhaler formulation loaded with alendronate solid lipid nanoparticles: solid-state characterization and aerosol dispersion performance.

Authors: Jafar Ezzati Nazhad Dolatabadi; Hamed Hamishehkar; Hadi Valizadeh
Journal: Drug Dev Ind Pharm Date: 2015-07-21 Impact factor: 3.225

21 in total

1. PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy.

Authors: Fereydoon Abedi-Gaballu; Gholamreza Dehghan; Maryam Ghaffari; Reza Yekta; Soheil Abbaspour-Ravasjani; Behzad Baradaran; Jafar Ezzati Nazhad Dolatabadi; Michael R Hamblin
Journal: Appl Mater Today Date: 2018-05-29

2. Investigation on Secondary Structure Alterations of Protein Drugs as an Indicator of Their Biological Activity Upon Thermal Exposure.

Authors: Farrukh Zeeshan; Misbah Tabbassum; Prashant Kesharwani
Journal: Protein J Date: 2019-10 Impact factor: 2.371

3. Preparation of Plasma Membrane Vesicles from Bone Marrow Mesenchymal Stem Cells for Potential Cytoplasm Replacement Therapy.

Authors: Li-Qun Xu; Mei-Jia Lin; Yun-Pan Li; Shuang Li; Shao-Jun Chen; Chi-Ju Wei
Journal: J Vis Exp Date: 2017-05-18 Impact factor: 1.355

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Authors: Farhad Jahanfar; Akbar Hasani; Dariush Shanebandi; Mohammad Rahmati; Hamed Hamishehkar
Journal: Adv Pharm Bull Date: 2016-09-25

Review 5. Comprehensive comparison of theranostic nanoparticles in breast cancer.

Authors: Amin Nikdouz; Nima Namarvari; Ramin Ghasemi Shayan; Arezoo Hosseini
Journal: Am J Clin Exp Immunol Date: 2022-02-15

6. The Effect of Particle Size on the Deposition of Solid Lipid Nanoparticles in Different Skin Layers: A Histological Study.

Authors: Zahra Mardhiah Adib; Saeed Ghanbarzadeh; Maryam Kouhsoltani; Ahmad Yari Khosroshahi; Hamed Hamishehkar
Journal: Adv Pharm Bull Date: 2016-03-17

7. Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics.

Authors: Yi-Ping Fang; Chih-Hung Chuang; Pao-Chu Wu; Yaw-Bin Huang; Cherng-Chyi Tzeng; Yeh-Long Chen; Ya-Ting Liu; Yi-Hung Tsai; Ming-Jun Tsai
Journal: Drug Des Devel Ther Date: 2016-03-04 Impact factor: 4.162