INTRODUCTION: In the present study, we observed differences in the clinical and haematological parameters in patients of MRSA and non MRSA acute osteoarticular infection. METHODOLOGY: For the patients of acute haematogenous osteomyelitis/septic arthritis, clinical features, haematological parameters and blood & aspirate cultures were recorded. RESULTS: Of 81 patients enrolled in the study, 61 were culture positive (22% MRSA). Statistically significant difference was found only in CRP (P < 0.001). ROC curve analysis shows that CRP levels of >13.9 mg/L, MRSA bone and joint infection could be predicted with 92.9% sensitivity and 79.1% specificity (AUC = 89.1). CONCLUSION: Estimation of serum CRP levels at the time of presentation can aid in distinguishing MRSA osteomyelitis from non MRSA one.
INTRODUCTION: In the present study, we observed differences in the clinical and haematological parameters in patients of MRSA and non MRSA acute osteoarticular infection. METHODOLOGY: For the patients of acute haematogenous osteomyelitis/septic arthritis, clinical features, haematological parameters and blood & aspirate cultures were recorded. RESULTS: Of 81 patients enrolled in the study, 61 were culture positive (22% MRSA). Statistically significant difference was found only in CRP (P < 0.001). ROC curve analysis shows that CRP levels of >13.9 mg/L, MRSA bone and joint infection could be predicted with 92.9% sensitivity and 79.1% specificity (AUC = 89.1). CONCLUSION: Estimation of serum CRP levels at the time of presentation can aid in distinguishing MRSA osteomyelitis from non MRSA one.
Authors: Sami Bouchoucha; Ghassen Drissi; Mehdi Trifa; Walid Saied; Chokri Ammar; Mahmoud Smida; Mohamed N Nessib; Nissaf Ben Alaya; Maher Ben Ghachem Journal: Tunis Med Date: 2012-06
Authors: Kelly L Vander Have; Boaz Karmazyn; Maneesh Verma; Michelle S Caird; Robert N Hensinger; Frances A Farley; John P Lubicky Journal: J Pediatr Orthop Date: 2009-12 Impact factor: 2.324