Literature DB >> 26232369

Metabolic Imaging as a Biomarker of Early Radiation Response in Tumors.

Stephen Y Lai1, C David Fuller2, Pratip K Bhattacharya3, Steven J Frank4.   

Abstract

(13)C-pyruvate hyperpolarized magnetic resonance imaging (HP-MRI) is emerging as a viable quantitative biomarker for solid tumor response and normal tissue toxicity after radiotherapy. This technology effectively predicts response related to metabolic agents or alterations in the tumor microenvironment, but challenges remain to be addressed to ensure successful translational implementation. See related article by Saito et al., p. 5073. ©2015 American Association for Cancer Research.

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Year:  2015        PMID： 26232369      PMCID： PMC4644683          DOI： 10.1158/1078-0432.CCR-15-1214

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  12 in total

1.  Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1- 13C]pyruvate and 13C magnetic resonance spectroscopic imaging.

Authors:  Sam E Day; Mikko I Kettunen; Murali Krishna Cherukuri; James B Mitchell; Martin J Lizak; H Douglas Morris; Shingo Matsumoto; Alan P Koretsky; Kevin M Brindle
Journal:  Magn Reson Med       Date:  2010-11-16       Impact factor: 4.668

2.  Towards adaptive IMRT sequencing for the MR-linac.

Authors:  Charis Kontaxis; G H Bol; J J W Lagendijk; B W Raaymakers
Journal:  Phys Med Biol       Date:  2015-03-06       Impact factor: 3.609

3.  Mapping metabolic changes associated with early Radiation Induced Lung Injury post conformal radiotherapy using hyperpolarized ¹³C-pyruvate Magnetic Resonance Spectroscopic Imaging.

Authors:  Kundan Thind; Michael D Jensen; Elaine Hegarty; Albert P Chen; Heeseung Lim; Francisco Martinez-Santiesteban; Jake Van Dyk; Eugene Wong; Timothy J Scholl; Giles E Santyr
Journal:  Radiother Oncol       Date:  2014-01-16       Impact factor: 6.280

Review 4.  Metabolic reprogramming: a cancer hallmark even warburg did not anticipate.

Authors:  Patrick S Ward; Craig B Thompson
Journal:  Cancer Cell       Date:  2012-03-20       Impact factor: 31.743

5.  Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization.

Authors:  Sarah E Bohndiek; Mikko I Kettunen; De-en Hu; Kevin M Brindle
Journal:  Cancer Res       Date:  2012-01-05       Impact factor: 12.701

6.  13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors.

Authors:  Keita Saito; Shingo Matsumoto; Yoichi Takakusagi; Masayuki Matsuo; H Douglas Morris; Martin J Lizak; Jeeva P Munasinghe; Nallathamby Devasahayam; Sankaran Subramanian; James B Mitchell; Murali C Krishna
Journal:  Clin Cancer Res       Date:  2015-02-11       Impact factor: 12.531

7.  Detection of radiation-induced lung injury using hyperpolarized (13)C magnetic resonance spectroscopy and imaging.

Authors:  K Thind; A Chen; L Friesen-Waldner; A Ouriadov; T J Scholl; M Fox; E Wong; J VanDyk; A Hope; G Santyr
Journal:  Magn Reson Med       Date:  2012-10-16       Impact factor: 4.668

8.  Chemical reaction-induced multi-molecular polarization (CRIMP).

Authors:  Y Lee; N M Zacharias; D Piwnica-Worms; P K Bhattacharya
Journal:  Chem Commun (Camb)       Date:  2014-11-07       Impact factor: 6.222

9.  Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation.

Authors:  Vlad C Sandulache; Heath D Skinner; Yuan Wang; Yunyun Chen; Cristina T Dodge; Thomas J Ow; James A Bankson; Jeffrey N Myers; Stephen Y Lai
Journal:  Mol Cancer Ther       Date:  2012-05-09       Impact factor: 6.261

10.  Evaluation of hyperpolarized [1-¹³C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time.

Authors:  Vlad C Sandulache; Yunyun Chen; Jaehyuk Lee; Ashley Rubinstein; Marc S Ramirez; Heath D Skinner; Christopher M Walker; Michelle D Williams; Ramesh Tailor; Laurence E Court; James A Bankson; Stephen Y Lai
Journal:  PLoS One       Date:  2014-01-27       Impact factor: 3.240
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  5 in total

1.  Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model.

Authors:  Vlad C Sandulache; Yunyun Chen; Heath D Skinner; Tongtong Lu; Lei Feng; Laurence E Court; Jeffrey N Myers; Raymond E Meyn; Clifton D Fuller; James A Bankson; Stephen Y Lai
Journal:  Mol Cancer Ther       Date:  2015-09-16       Impact factor: 6.261

2.  Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma.

Authors:  Valentina Di Gialleonardo; Hannah N Aldeborgh; Vesselin Miloushev; Kelly M Folkers; Kristin Granlund; William D Tap; Jason S Lewis; Wolfgang A Weber; Kayvan R Keshari
Journal:  Cancer Res       Date:  2017-04-06       Impact factor: 12.701

3.  Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress.

Authors:  Frances L Byrne; Ellen M Olzomer; Gabriella R Marriott; Lake-Ee Quek; Alice Katen; Jacky Su; Marin E Nelson; Gene Hart-Smith; Mark Larance; Veronica F Sebesfi; Jeff Cuff; Gabriella E Martyn; Elizabeth Childress; Stephanie J Alexopoulos; Ivan K Poon; Maree C Faux; Antony W Burgess; Glen Reid; Joshua A McCarroll; Webster L Santos; Kate Gr Quinlan; Nigel Turner; Daniel J Fazakerley; Naresh Kumar; Kyle L Hoehn
Journal:  Redox Biol       Date:  2019-11-05       Impact factor: 11.799

Review 4.  Laser-driven radiation: Biomarkers for molecular imaging of high dose-rate effects.

Authors:  Theodor Asavei; Mariana Bobeica; Viorel Nastasa; Gina Manda; Florin Naftanaila; Ovidiu Bratu; Dan Mischianu; Mihail O Cernaianu; Petru Ghenuche; Diana Savu; Dan Stutman; Kazuo A Tanaka; Mihai Radu; Domenico Doria; Paul R Vasos
Journal:  Med Phys       Date:  2019-08-29       Impact factor: 4.071

Review 5.  Hyperpolarized Magnetic Resonance and Artificial Intelligence: Frontiers of Imaging in Pancreatic Cancer.

Authors:  José S Enriquez; Yan Chu; Shivanand Pudakalakatti; Kang Lin Hsieh; Duncan Salmon; Prasanta Dutta; Niki Zacharias Millward; Eugene Lurie; Steven Millward; Florencia McAllister; Anirban Maitra; Subrata Sen; Ann Killary; Jian Zhang; Xiaoqian Jiang; Pratip K Bhattacharya; Shayan Shams
Journal:  JMIR Med Inform       Date:  2021-06-17
  5 in total

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