Literature DB >> 26232217

You Down With ETC? Yeah, You Know D!

Jonathan G Van Vranken1, Jared Rutter2.   

Abstract

Although the mitochondrial electron transport chain (ETC) is best known for its role in ATP synthesis, two studies, Sullivan et al. and Birsoy et al., conclude that its only essential function in proliferating cells is making aspartate (D).
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Year:  2015        PMID： 26232217     DOI： 10.1016/j.cell.2015.07.027

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells.

Authors:  Deven Patel; Deepak Menon; Elyssa Bernfeld; Victoria Mroz; Sampada Kalan; Diego Loayza; David A Foster
Journal:  J Biol Chem       Date:  2016-02-26       Impact factor: 5.157

2.  Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts.

Authors:  Huabo Wang; Jie Lu; Sucheta Kulkarni; Weiqi Zhang; Joanna E Gorka; Jordan A Mandel; Eric S Goetzman; Edward V Prochownik
Journal:  J Biol Chem       Date:  2019-02-12       Impact factor: 5.157

Review 3.  Stressed to death: Mitochondrial stress responses connect respiration and apoptosis in cancer.

Authors:  Jacob M Winter; Tarun Yadav; Jared Rutter
Journal:  Mol Cell       Date:  2022-08-11       Impact factor: 19.328

4.  Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism.

Authors:  Walter W Chen; Elizaveta Freinkman; Tim Wang; Kıvanç Birsoy; David M Sabatini
Journal:  Cell       Date:  2016-08-25       Impact factor: 41.582

Review 5.  Metabolic rewiring in melanoma.

Authors:  B I Ratnikov; D A Scott; A L Osterman; J W Smith; Z A Ronai
Journal:  Oncogene       Date:  2016-06-06       Impact factor: 9.867

6.  Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction.

Authors:  Chun-Ting Cheng; Yue Qi; Yi-Chang Wang; Kevin K Chi; Yiyin Chung; Ching Ouyang; Yun-Ru Chen; Myung Eun Oh; Xiangpeng Sheng; Yulong Tang; Yun-Ru Liu; H Helen Lin; Ching-Ying Kuo; Dustin Schones; Christina M Vidal; Jenny C-Y Chu; Hung-Jung Wang; Yu-Han Chen; Kyle M Miller; Peiguo Chu; Yun Yen; Lei Jiang; Hsing-Jien Kung; David K Ann
Journal:  Commun Biol       Date:  2018-10-26

7.  Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells.

Authors:  Sebastián Fuentes-Retamal; Cristian Sandoval-Acuña; Liliana Peredo-Silva; Daniela Guzmán-Rivera; Mario Pavani; Natalia Torrealba; Jaroslav Truksa; Vicente Castro-Castillo; Mabel Catalán; Ulrike Kemmerling; Félix A Urra; Jorge Ferreira
Journal:  Cells       Date:  2020-02-11       Impact factor: 6.600

Review 8.  Amino Acid Metabolism in Cancer Drug Resistance.

Authors:  Hee-Chan Yoo; Jung-Min Han
Journal:  Cells       Date:  2022-01-02       Impact factor: 6.600

9.  SLC1A3 contributes to L-asparaginase resistance in solid tumors.

Authors:  Jianhui Sun; Remco Nagel; Esther A Zaal; Alejandro Piñeiro Ugalde; Ruiqi Han; Natalie Proost; Ji-Ying Song; Abhijeet Pataskar; Artur Burylo; Haigen Fu; Gerrit J Poelarends; Marieke van de Ven; Olaf van Tellingen; Celia R Berkers; Reuven Agami
Journal:  EMBO J       Date:  2019-09-16       Impact factor: 11.598
  9 in total

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