Literature DB >> 26231189

Epithelial-myoepithelial carcinoma of lacrimal gland from an ex pleomorphic adenoma.

Bhanu Prasad Venkatesulu1, Sushmita Pathy1, Archana George Vallonthaiel2, Bhavna Chawla3.   

Abstract

A 47-year-old man with a history of recurrent pleomorphic adenoma of the right lacrimal gland presented with rapid onset of a swelling in the right orbit. Initial imaging with CT showed that the swelling was grossly involving the extraocular muscles. Hence we had a suspicion of malignant transformation, so a radical approach in the form of right orbital exenteration with anterior skull base resection and temporalis muscle reconstruction was taken. Postoperative histology revealed epithelial-myoepithelial carcinoma, with immunopositivity for epithelial and myoepithelial components. Adjuvant radiation of 60 Gy was given with three-dimensional CT-based planning. This case portrays the importance of adjuvant treatment in recurrent pleomorphic adenoma and chance of malignant transformation in rare histologies. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26231189      PMCID: PMC4521531          DOI: 10.1136/bcr-2015-210795

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

1.  Primary epithelial-myoepithelial carcinoma of the lacrimal gland.

Authors:  Wai-Man Chan; David T L Liu; Lawrence Y M Lam; Paul C L Choi; Carmen K M Chan; Dennis S C Lam; Nongnart R Chan
Journal:  Arch Ophthalmol       Date:  2004-11

2.  Unusual carcinomas of the lacrimal gland: epithelial-myoepithelial carcinoma and myoepithelial carcinoma.

Authors:  Damrong Wiwatwongwana; Kenneth W Berean; Peter J Dolman; Jack Rootman; Valerie A White
Journal:  Arch Ophthalmol       Date:  2009-08

3.  Epithelial-Myoepithelial Carcinoma of the Lacrimal Gland 14 Years After En Bloc Resection of a Pleomorphic Lacrimal Gland Adenoma.

Authors:  Allan C Pieroni Gonçalves; Patricia Picciarelli de Lima; Mario L R Monteiro
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2016 Mar-Apr       Impact factor: 1.746

4.  Clear cell epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the lacrimal gland.

Authors:  M L Ostrowski; R L Font; J Halpern; E Nicolitz; R Barnes
Journal:  Ophthalmology       Date:  1994-05       Impact factor: 12.079

5.  Outcomes of malignant tumors of the lacrimal apparatus: the University of Texas MD Anderson Cancer Center experience.

Authors:  Heath D Skinner; Adam S Garden; David I Rosenthal; K Kian Ang; William H Morrison; Bita Esmaeli; Chelsea C Pinnix; Steven J Frank
Journal:  Cancer       Date:  2011-01-10       Impact factor: 6.860

6.  Epithelial lacrimal gland tumors: pathologic classification and current understanding.

Authors:  Ezekiel Weis; Jack Rootman; Thomas J Joly; Kenneth W Berean; Hind M Al-Katan; Sylvia Pasternak; Giulio Bonavolontà; Diego Strianese; Peerooz Saeed; Kenneth A Feldman; Sumalee Vangveeravong; Jocelyne S Lapointe; Valerie A White
Journal:  Arch Ophthalmol       Date:  2009-08

7.  Epithelial-myoepithelial carcinoma of the lacrimal gland: a rare case.

Authors:  Geetika Singh; Mehar Chand Sharma; Shipra Agarwal; G Lakshmi Prasad; Shashwat Mishra; Man Mohan Singh; Ajay Garg; Vaishali Suri; Chitra Sarkar
Journal:  Ann Diagn Pathol       Date:  2011-05-04       Impact factor: 2.090

8.  DNA content and proliferative activity of myoepitheliomas.

Authors:  A el-Naggar; J G Batsakis; M A Luna; H Goepfert; M E Tortoledo
Journal:  J Laryngol Otol       Date:  1989-12       Impact factor: 1.469

9.  Clinicopathologic review of 142 cases of lacrimal gland lesions.

Authors:  C L Shields; J A Shields; R C Eagle; J P Rathmell
Journal:  Ophthalmology       Date:  1989-04       Impact factor: 12.079

10.  Salivary gland malignant myoepithelioma: a clinicopathologic and immunohistochemical study of ten cases.

Authors:  T Nagao; I Sugano; Y Ishida; Y Tajima; O Matsuzaki; A Konno; Y Kondo; K Nagao
Journal:  Cancer       Date:  1998-10-01       Impact factor: 6.860

  10 in total
  4 in total

1.  Primary poorly differentiated lacrimal gland adenocarcinoma in left ocular region: A rare case report.

Authors:  Fan Xia; Wenwu Ling; Jing Zhang; Yifan Zhang; Xuelei Ma
Journal:  Medicine (Baltimore)       Date:  2018-09       Impact factor: 1.817

2.  Epithelial-Myoepithelial Carcinoma of the Lacrimal Sac and Literature Review of the Lacrimal System.

Authors:  Dhruv Sharma; Ashley Neiweem; Kyle Davis; Mark Prendes; Rao Chundury; Elisa Illing
Journal:  Allergy Rhinol (Providence)       Date:  2020-04-20

3.  Retrospective Analysis of Clinicopathological Characteristics of Lacrimal Gland Pleomorphic Adenoma and Mechanism of Tumorigenesis by the Imbalance Between Apoptosis and Proliferation.

Authors:  Meng Lv; Zhi-Jun Dong; Yue-Xin Tong; Tian Li; Yan Hei; Xin-Ji Yang; Wei-Li Dong
Journal:  Med Sci Monit       Date:  2021-03-19

4.  Ductal Adenocarcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland: a Rare and Morbid Malignancy.

Authors:  Prashanth Ashok Kumar; Shweta Paulraj; Kanish Mirchia; Seung Shin Hahn; Abirami Sivapiragasam
Journal:  Case Rep Oncol Med       Date:  2020-02-03
  4 in total

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