Literature DB >> 26231186

A novel approach to optimise glycaemic control in insulin users.

Eran Bashan1, Roy Harper2, Yixi Bi3, Israel Hodish4.   

Abstract

Insulin therapy has been available for almost a century. However, its success rate is still disappointing where the majority of users sustain harmfully elevated glycated haemoglobin (HbA1c) levels. The key element essential for effective and safe insulin therapy is frequent dosage titration to overcome constant variations in insulin requirements. In reality, dosage titration is done sporadically during clinic visits. A scalable solution to this problem is being reviewed. A diabetes nurses service improves glycaemic control without overburdening the health system. The service relies on a handheld device, which provides patients with an insulin dose recommendation for each injection while using the device to monitor glucose. Similar to the approach providers use during clinical encounters, the device analyses stored glucose trends and constantly titrates insulin dosage without care providers' supervision. In this report, we describe the logic behind the technology by providing examples from users. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26231186      PMCID: PMC4521526          DOI: 10.1136/bcr-2015-209356

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  24 in total

1.  Is glycemic control improving in U.S. adults?

Authors:  Thomas J Hoerger; Joel E Segel; Edward W Gregg; Jinan B Saaddine
Journal:  Diabetes Care       Date:  2007-10-12       Impact factor: 19.112

2.  Relationship between glycemic control and diabetes-related hospital costs in patients with type 1 or type 2 diabetes mellitus.

Authors:  Joseph Menzin; Jonathan R Korn; Joseph Cohen; Francis Lobo; Bin Zhang; Mark Friedman; Peter J Neumann
Journal:  J Manag Care Pharm       Date:  2010-05

3.  The effort required to achieve and maintain optimal glycemic control.

Authors:  Elyse S Rosenthal; Eran Bashan; William H Herman; Israel Hodish
Journal:  J Diabetes Complications       Date:  2011-03-01       Impact factor: 2.852

4.  Are glucose readings sufficient to adjust insulin dosage?

Authors:  Eran Bashan; William H Herman; Israel Hodish
Journal:  Diabetes Technol Ther       Date:  2011-01       Impact factor: 6.118

5.  A clinical trial of continuous subcutaneous insulin infusion versus multiple daily injections in older adults with type 2 diabetes.

Authors:  William H Herman; Liza L Ilag; Susan L Johnson; Catherine L Martin; Joyce Sinding; Abdulaziz Al Harthi; Cynthia D Plunkett; Frankie B LaPorte; Ray Burke; Morton B Brown; Jeffery B Halter; Philip Raskin
Journal:  Diabetes Care       Date:  2005-07       Impact factor: 19.112

6.  Refill compliance in type 2 diabetes mellitus: a predictor of switching to insulin therapy?

Authors:  José A Spoelstra; Ronald P Stolk; Eibert R Heerdink; Olaf H Klungel; Joëlle A Erkens; Hubert G M Leufkens; Diederick E Grobbee
Journal:  Pharmacoepidemiol Drug Saf       Date:  2003-03       Impact factor: 2.890

7.  Treat-to-target insulin titration algorithms when initiating long or intermediate acting insulin in type 2 diabetes.

Authors:  Poul Strange
Journal:  J Diabetes Sci Technol       Date:  2007-07

8.  Three-year efficacy of complex insulin regimens in type 2 diabetes.

Authors:  Rury R Holman; Andrew J Farmer; Melanie J Davies; Jonathan C Levy; Julie L Darbyshire; Joanne F Keenan; Sanjoy K Paul
Journal:  N Engl J Med       Date:  2009-10-22       Impact factor: 91.245

9.  Why don't diabetes patients achieve recommended risk factor targets? Poor adherence versus lack of treatment intensification.

Authors:  Julie A Schmittdiel; Connie S Uratsu; Andrew J Karter; Michele Heisler; Usha Subramanian; Carol M Mangione; Joe V Selby
Journal:  J Gen Intern Med       Date:  2008-03-04       Impact factor: 5.128

10.  Economic costs of diabetes in the U.S. in 2012.

Authors: 
Journal:  Diabetes Care       Date:  2013-03-06       Impact factor: 19.112

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  3 in total

1.  Automated insulin dosing guidance to optimise insulin management in patients with type 2 diabetes: a multicentre, randomised controlled trial.

Authors:  Richard M Bergenstal; Mary Johnson; Rebecca Passi; Anuj Bhargava; Natalie Young; Davida F Kruger; Eran Bashan; Stanley G Bisgaier; Deanna J Marriott Isaman; Israel Hodish
Journal:  Lancet       Date:  2019-02-23       Impact factor: 79.321

2.  Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses.

Authors:  John E Schneider; Anjani Parikh; Ivana Stojanovic
Journal:  J Health Econ Outcomes Res       Date:  2018-02-20

3.  Insulin therapy for type 2 diabetes - are we there yet? The d-Nav® story.

Authors:  I Hodish
Journal:  Clin Diabetes Endocrinol       Date:  2018-04-10
  3 in total

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