Literature DB >> 26229725

Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation.

P C Manyike1, C Okike2, N B Onyire1, J M Chinawa3, J U Austin-Abu4.   

Abstract

Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who presented with high-grade intermittent fever associated with multiple convulsions and prolonged coma. He regained consciousness after 12 days of treatment with intravenous quinine but was found to have blindness, sensory-neural deafness and extrapyramidal sign. This extrapyramidal sign regressed following treatment with chlorpromazine. He also regained his sight and auditory function before he was discharged though not completely. This report is aimed at emphasizing these rare complications of cerebral malaria as well as reminding clinicians working in malaria endemic areas of the world on the need for early diagnosis and prompt treatment.

Entities:  

Keywords:  Blindness; Cerebral malaria; Coma

Year:  2015        PMID: 26229725      PMCID: PMC4512129          DOI: 10.4103/2141-9248.160183

Source DB:  PubMed          Journal:  Ann Med Health Sci Res        ISSN: 2141-9248


  5 in total

1.  Global malaria mortality between 1980 and 2010: a systematic analysis.

Authors:  Christopher J L Murray; Lisa C Rosenfeld; Stephen S Lim; Kathryn G Andrews; Kyle J Foreman; Diana Haring; Nancy Fullman; Mohsen Naghavi; Rafael Lozano; Alan D Lopez
Journal:  Lancet       Date:  2012-02-04       Impact factor: 79.321

2.  Rosetting characteristics of uninfected erythrocytes from healthy individuals and malaria patients.

Authors:  K T Chotivanich; R Udomsangpetch; B Pipitaporn; B Angus; Y Suputtamongkol; S Pukrittayakamee; N J White
Journal:  Ann Trop Med Parasitol       Date:  1998-01

Review 3.  Neurological manifestations of malaria : an update.

Authors:  R K Garg; B Karak; S Misra
Journal:  Neurol India       Date:  1999-06       Impact factor: 2.117

Review 4.  Neurological complications of malaria.

Authors:  N Senanayake; G C Román
Journal:  Southeast Asian J Trop Med Public Health       Date:  1992-12       Impact factor: 0.267

Review 5.  Neurological sequelae of cerebral malaria in children.

Authors:  D R Brewster; D Kwiatkowski; N J White
Journal:  Lancet       Date:  1990-10-27       Impact factor: 79.321

  5 in total

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