Literature DB >> 26228496

Effectiveness of hyaluronic acid in post-tonsillectomy pain relief and wound healing: a prospective, double-blind, controlled clinical study.

Deniz Hancı1, Huseyin Altun2.   

Abstract

OBJECTIVES: To find the effectiveness of hyaluronic acid in post-tonsillectomy pain relief and wound healing.
METHODS: Fifty patients were included in this prospective, double-blind, controlled clinical study (20 males, 30 females mean age of 13.56 years). Hyaluronic acid was applied to one side and the other side was used as a control during tonsillectomy. Therefore, the same patient evaluated and scored the post-tonsillectomy pain, excluding individual bias.
RESULTS: Results indicated that patients had significantly lower pain scores for hyaluronic acid treated side (p<0.001). At the end of two weeks follow-up period, the wound in the hyaluronic acid side was almost completely healed, indicating that the healing was faster with hyaluronic acid compared to control side (p<0.001).
CONCLUSION: Hyaluronic acid could be recommended as an effective treatment for the management of post-tonsillectomy pain and wound healing.
Copyright © 2015. Published by Elsevier Ireland Ltd.

Entities:  

Keywords:  Double-blind study; Hyaluronic acid; Pain; Tonsillectomy; Wound healing

Mesh:

Substances:

Year:  2015        PMID: 26228496     DOI: 10.1016/j.ijporl.2015.07.016

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  7 in total

1.  Methylprednisolone and Hyaluronic Acid versus Each Agent Alone to Control Complication of Impacted Wisdom Removal.

Authors:  Alaa Abdelqader Altaweel; Abd El-Hamid Gaber; Mahmoud Zuhair Alnaffar; Elham Ahmed Alshomrani; Rahaf Asaad Alrehaili; Rahaf Abdulmoeen Alshaikh; Jumana Nader Baeshin; Elaf Sami Al-Akhdar
Journal:  Evid Based Complement Alternat Med       Date:  2022-03-24       Impact factor: 2.629

2.  Posterior pillar mucosal suspension technique for posttonsillectomy pain and wound healing: a prospective, randomized, controlled trial.

Authors:  Fatih Alper Akcan; Yusuf Dündar
Journal:  Eur Arch Otorhinolaryngol       Date:  2018-09-26       Impact factor: 2.503

Review 3.  [Application of medical biomaterials in prevention and treatment of tendon adhesion].

Authors:  Mingmin Zhang; Gaohong Ren
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2020-08-15

4.  Effects of hyaluronic acid on bleeding following third molar extraction.

Authors:  Gokhan Gocmen; Sertac Aktop; Burcin Tüzüner; Bahar Goker; Aysen Yarat
Journal:  J Appl Oral Sci       Date:  2017 Mar-Apr       Impact factor: 2.698

5.  Is Ginger Effective in Reducing Post-tonsillectomy Morbidity? A Prospective Randomised Clinical Trial.

Authors:  İlker Koçak; Cemil Yücepur; Ozan Gökler
Journal:  Clin Exp Otorhinolaryngol       Date:  2017-09-08       Impact factor: 3.372

6.  Fabrication of KR-12 peptide-containing hyaluronic acid immobilized fibrous eggshell membrane effectively kills multi-drug-resistant bacteria, promotes angiogenesis and accelerates re-epithelialization.

Authors:  Menglong Liu; Tengfei Liu; Xiaorong Zhang; Zhiwen Jian; Hesheng Xia; Jiacai Yang; Xiaohong Hu; Malcolm Xing; Gaoxing Luo; Jun Wu
Journal:  Int J Nanomedicine       Date:  2019-05-07

Review 7.  Generation of novel hyaluronic acid biomaterials for study of pain in third molar intervention: a review.

Authors:  Nadia Sultana Shuborna; Teeranut Chaiyasamut; Watus Sakdajeyont; Chakorn Vorakulpipat; Manus Rojvanakarn; Natthamet Wongsirichat
Journal:  J Dent Anesth Pain Med       Date:  2019-02-28
  7 in total

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