Literature DB >> 26227961

Structural basis of the Norrin-Frizzled 4 interaction.

Guobo Shen1,2, Jiyuan Ke3, Zhizhi Wang1, Zhihong Cheng1, Xin Gu3, Yuquan Wei2, Karsten Melcher3, H Eric Xu3,4, Wenqing Xu1.   

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Year:  2015        PMID： 26227961      PMCID： PMC4559814          DOI： 10.1038/cr.2015.92

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


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  12 in total

1.  Frizzled receptor dimerization is sufficient to activate the Wnt/beta-catenin pathway.

Authors:  Clémence Carron; Aude Pascal; Alexandre Djiane; Jean-Claude Boucaut; De-Li Shi; Muriel Umbhauer
Journal:  J Cell Sci       Date:  2003-05-06       Impact factor: 5.285

Review 2.  The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease.

Authors:  Xin Ye; Yanshu Wang; Jeremy Nathans
Journal:  Trends Mol Med       Date:  2010-08-03       Impact factor: 11.951

3.  Mutational analysis of Norrin-Frizzled4 recognition.

Authors:  Philip M Smallwood; John Williams; Qiang Xu; Daniel J Leahy; Jeremy Nathans
Journal:  J Biol Chem       Date:  2006-12-06       Impact factor: 5.157

4.  Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization.

Authors:  Ajamete Kaykas; Julia Yang-Snyder; Madeleine Héroux; Kavita V Shah; Michel Bouvier; Randall T Moon
Journal:  Nat Cell Biol       Date:  2003-12-14       Impact factor: 28.824

5.  TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling.

Authors:  Harald J Junge; Stacey Yang; Jeremy B Burton; Kim Paes; Xiao Shu; Dorothy M French; Mike Costa; Dennis S Rice; Weilan Ye
Journal:  Cell       Date:  2009-10-16       Impact factor: 41.582

6.  Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.

Authors:  Qiang Xu; Yanshu Wang; Alain Dabdoub; Philip M Smallwood; John Williams; Chad Woods; Matthew W Kelley; Li Jiang; William Tasman; Kang Zhang; Jeremy Nathans
Journal:  Cell       Date:  2004-03-19       Impact factor: 41.582

7.  Structural basis of Wnt recognition by Frizzled.

Authors:  Claudia Y Janda; Deepa Waghray; Aron M Levin; Christoph Thomas; K Christopher Garcia
Journal:  Science       Date:  2012-05-31       Impact factor: 47.728

8.  Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation.

Authors:  Josipa Bilic; Ya-Lin Huang; Gary Davidson; Timo Zimmermann; Cristina-Maria Cruciat; Mariann Bienz; Christof Niehrs
Journal:  Science       Date:  2007-06-15       Impact factor: 47.728

9.  Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.

Authors:  Tao-Hsin Chang; Fu-Lien Hsieh; Matthias Zebisch; Karl Harlos; Jonathan Elegheert; E Yvonne Jones
Journal:  Elife       Date:  2015-07-09       Impact factor: 8.140

10.  Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex.

Authors:  Jiyuan Ke; Kaleeckal G Harikumar; Clara Erice; Chen Chen; Xin Gu; Liren Wang; Naomi Parker; Zhihong Cheng; Wenqing Xu; Bart O Williams; Karsten Melcher; Laurence J Miller; H Eric Xu
Journal:  Genes Dev       Date:  2013-11-01       Impact factor: 11.361
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  20 in total

1.  Intrinsic disorder in spondins and some of their interacting partners.

Authors:  Oluwole Alowolodu; Gbemisola Johnson; Lamis Alashwal; Iqbal Addou; Irina V Zhdanova; Vladimir N Uversky
Journal:  Intrinsically Disord Proteins       Date:  2016-12-15

2.  TSPAN12 Is a Norrin Co-receptor that Amplifies Frizzled4 Ligand Selectivity and Signaling.

Authors:  Maria B Lai; Chi Zhang; Jianli Shi; Verity Johnson; Lavan Khandan; John McVey; Michael W Klymkowsky; Zhe Chen; Harald J Junge
Journal:  Cell Rep       Date:  2017-06-27       Impact factor: 9.423

3.  Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding.

Authors:  Aaron H Nile; Susmith Mukund; Karen Stanger; Weiru Wang; Rami N Hannoush
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-04       Impact factor: 11.205

4.  Identification and functional analysis of CORIN variants in hypertensive patients.

Authors:  Yue Zhang; Tiantian Zhou; Yayan Niu; Meiling He; Can Wang; Meng Liu; Junhua Yang; Yonghong Zhang; Jianping Zhou; Koichi Fukuda; Jun Qin; Ningzheng Dong; Qingyu Wu
Journal:  Hum Mutat       Date:  2017-09-26       Impact factor: 4.878

Review 5.  Assembly and architecture of the Wnt/β-catenin signalosome at the membrane.

Authors:  Zachary J DeBruine; H E Xu; Karsten Melcher
Journal:  Br J Pharmacol       Date:  2017-10-18       Impact factor: 8.739

6.  Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation.

Authors:  Chris Cho; Philip M Smallwood; Jeremy Nathans
Journal:  Neuron       Date:  2017-08-10       Impact factor: 17.173

7.  Functional role of the Frizzled linker domain in the Wnt signaling pathway.

Authors:  Seung-Bum Ko; Emiko Mihara; Yedarm Park; Kyeonghwan Roh; Chanhee Kang; Junichi Takagi; Injin Bang; Hee-Jung Choi
Journal:  Commun Biol       Date:  2022-05-05

8.  Mutation spectrum of the Norrie disease pseudoglioma (NDP) gene in Indian patients with FEVR.

Authors:  Ganeswara Rao Musada; Subhadra Jalali; Anjli Hussain; Anupama Reddy Chururu; Pramod Reddy Gaddam; Subhabrata Chakrabarti; Inderjeet Kaur
Journal:  Mol Vis       Date:  2016-05-16       Impact factor: 2.367

9.  Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function.

Authors:  Chi Zhang; Maria B Lai; Lavan Khandan; Lindsey A Lee; Zhe Chen; Harald J Junge
Journal:  Nat Commun       Date:  2017-07-04       Impact factor: 14.919

10.  Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.

Authors:  Xianjun Zhang; Fei Zhao; Yiran Wu; Jun Yang; Gye Won Han; Suwen Zhao; Andrii Ishchenko; Lintao Ye; Xi Lin; Kang Ding; Venkatasubramanian Dharmarajan; Patrick R Griffin; Cornelius Gati; Garrett Nelson; Mark S Hunter; Michael A Hanson; Vadim Cherezov; Raymond C Stevens; Wenfu Tan; Houchao Tao; Fei Xu
Journal:  Nat Commun       Date:  2017-05-17       Impact factor: 14.919
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