Literature DB >> 26226306

Challenges in antibody-drug conjugate discovery: a bioconjugation and analytical perspective.

Chetana Rao1, Vangipuram S Rangan1, Shrikant Deshpande1.   

Abstract

Keywords:  antibody–drug conjugate; conjugation; drug–antibody ratio; payload; payload linker

Mesh：

Substances：

Year:  2015        PMID： 26226306     DOI： 10.4155/bio.15.81

Source DB:  PubMed          Journal:  Bioanalysis        ISSN： 1757-6180            Impact factor:   2.681


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  2 in total

1.  Rapid and Simultaneous Characterization of Drug Conjugation in Heavy and Light Chains of a Monoclonal Antibody Revealed by High-Resolution Ion Mobility Separations in SLIM.

Authors:  Gabe Nagy; Isaac K Attah; Christopher R Conant; Weijing Liu; Sandilya V B Garimella; Harsha P Gunawardena; Jared B Shaw; Richard D Smith; Yehia M Ibrahim
Journal:  Anal Chem       Date:  2020-03-17       Impact factor: 6.986

Review 2.  Antibody drug conjugate: the "biological missile" for targeted cancer therapy.

Authors:  Zhiwen Fu; Shijun Li; Sifei Han; Chen Shi; Yu Zhang
Journal:  Signal Transduct Target Ther       Date:  2022-03-22
  2 in total

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