Literature DB >> 26225142

Negative Pressure, a "Solution" in the Treatment of Infected Knee Prosthesis?

Razvan Ene1, Zsombor Panti1, Emanuel Albu2, Patricia Ene3, Monica Mihaela Cirstoiu4, Florin Catalin Cirstoiu1.   

Abstract

INTRODUCTION: Negative-pressure wound therapy is a therapeutic technique that uses a vacuum dressing in order to promote healing in acute or chronic wounds. The continued vacuum draws out fluid from the wound and increases blood flow to the area. The aim of this study was to establish the effectiveness of negative pressure therapy increasing this way the chances of rehabilitation after knee prosthesis infections. MATERIAL AND
METHOD: 11 patients with septic complications after total knee joint replacement were involved into this study, from the Department of Orthopaedic and Traumatology of Bucharest Emergency University Hospital. In all of the cases negative pressure wound treatment was applied. The surgical approach was chosen according to the surgeon's preferences or along the pre-existing surgical approach. RESULTS AND DISCUSSIONS: Time from the knee arthroplasty to the clinical and biological manifestation of septic complications was about 35 days with limits between 21 and 42 days. In most cases we managed to keep the implant, the outcome obviously being conditioned by using the negative pressure. Knee infections are still a hazardous problem in orthopedic surgery. Negative-pressure system increased the granulation tissue formation and the local blood flow and enhanced the bacterial clearance function.
CONCLUSIONS: The clinical outcome in our cases indicates that the Negative-Pressure Wound Therapy can be a valuable contribution to the treatment of knee joint infections.

Entities:  

Keywords:  infection; knee prosthesis; negative-pressure wound therapy; vacuum-assisted closure

Year:  2015        PMID: 26225142      PMCID: PMC4496767     

Source DB:  PubMed          Journal:  Maedica (Buchar)        ISSN: 1841-9038


  13 in total

1.  Factors associated with positive outcomes in 131 patients treated with gauze-based negative pressure wound therapy.

Authors:  Raymond Dunn; Theresa Hurd; P Chadwick; Julien Cote; John Cockwill; Trevor Mole; Jennifer Smith
Journal:  Int J Surg       Date:  2010-12-25       Impact factor: 6.071

Review 2.  Update on negative-pressure wound therapy.

Authors:  Dennis P Orgill; Lauren R Bayer
Journal:  Plast Reconstr Surg       Date:  2011-01       Impact factor: 4.730

Review 3.  Vacuum-assisted closure: state of basic research and physiologic foundation.

Authors:  Michael J Morykwas; Jordan Simpson; Kally Punger; Anne Argenta; Lieveke Kremers; Joseph Argenta
Journal:  Plast Reconstr Surg       Date:  2006-06       Impact factor: 4.730

Review 4.  A systematic review of topical negative pressure therapy for acute and chronic wounds.

Authors:  D T Ubbink; S J Westerbos; E A Nelson; H Vermeulen
Journal:  Br J Surg       Date:  2008-06       Impact factor: 6.939

5.  Effects of vacuum-assisted closure on wound microcirculation: an experimental study.

Authors:  Shao-Zong Chen; Jing Li; Xue-Yong Li; Long-Shun Xu
Journal:  Asian J Surg       Date:  2005-07       Impact factor: 2.767

6.  [Influence of negative pressure wound therapy on the angiogenesis of wounds in diabetic rats].

Authors:  Xiao-qiang Li; Da-hai Hu; Yang Liu; Yao-jun Wang; Fu Han; Xiao-long Hu; Na Li; Yue Zhang; Xiao-zhi Bai
Journal:  Zhonghua Shao Shang Za Zhi       Date:  2013-10

7.  Negative pressure wound therapy literature review of efficacy, cost effectiveness, and impact on patients' quality of life in chronic wound management and its implementation in the United kingdom.

Authors:  Diaa Othman
Journal:  Plast Surg Int       Date:  2012-05-30

8.  Negative pressure wound therapy - a review of its uses in orthopaedic trauma.

Authors:  Sven Putnis; Wasim S Khan; James M-L Wong
Journal:  Open Orthop J       Date:  2014-06-27

9.  The efficacy of negative pressure wound therapy on chemotherapeutic extravasation ulcers: An experimental study.

Authors:  Evren Iscı; Halil I Canter; Mehmet Dadacı; Pergin Atılla; Ayse N Cakar; Abdullah Kecık
Journal:  Indian J Plast Surg       Date:  2014 Sep-Dec

10.  Effects of negative pressure wound therapy on mesenchymal stem cells proliferation and osteogenic differentiation in a fibrin matrix.

Authors:  Jin Zhu; Aixi Yu; Baiwen Qi; Zonghuan Li; Xiang Hu
Journal:  PLoS One       Date:  2014-09-12       Impact factor: 3.240

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  4 in total

1.  Use of muscular flaps for the treatment of knee prosthetic joint infection: A systematic review.

Authors:  Giuseppe Rovere; Amarildo Smakaj; Sara Calori; Marco Barbaliscia; Antonio Ziranu; Elisabetta Pataia; Giulio Maccauro; Domenico De Mauro; Francesco Liuzza
Journal:  Orthop Rev (Pavia)       Date:  2022-04-25

2.  Murine Model Imitating Chronic Wound Infections for Evaluation of Antimicrobial Photodynamic Therapy Efficacy.

Authors:  Grzegorz Fila; Kamola Kasimova; Yaxal Arenas; Joanna Nakonieczna; Mariusz Grinholc; Krzysztof P Bielawski; Lothar Lilge
Journal:  Front Microbiol       Date:  2016-08-09       Impact factor: 5.640

3.  INCISIONAL NEGATIVE-PRESSURE WOUND THERAPY IN REVISION TOTAL HIP ARTHROPLASTY DUE TO INFECTION.

Authors:  Helder de Souza Miyahara; Felipe Ribeiro Serzedello; Leandro Ejnisman; Ana Lúcia Lei Munhoz Lima; José Ricardo Negreiros Vicente; Camilo Partezani Helito
Journal:  Acta Ortop Bras       Date:  2018       Impact factor: 0.513

Review 4.  Wound debridement products and techniques: clinical examples and literature review.

Authors:  Marcela Nowak; Dorota Mehrholz; Wioletta Barańska-Rybak; Roman J Nowicki
Journal:  Postepy Dermatol Alergol       Date:  2022-07-14       Impact factor: 1.664

  4 in total

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