Literature DB >> 26225044

Keratocystic Odontogenic Tumor (KCOT/OKC)-Clinical Guidelines for Resection.

Gary Warburton1, Amro Shihabi1, Robert A Ord1.   

Abstract

PURPOSE: There is no clinical consensus for the treatment of Keratocystic Odontogenic Tumor (KCOT). KCOTs are regarded as benign aggressive tumors and resection is usually considered as a last option. We review the clinical indications for resection based on a case series.
METHODS: This is a retrospective study of patients with KCOT treated in a single unit over 17 years. Eighty patients were identified, of which 12 (15 %) underwent resection. The remaining 68 patients were managed by enucleation and curettage, enucleation with peripheral ostectomy, or decompression with secondary enucleation. Data extracted includes gender, age, race, location, previous treatment for the lesion, surgery and outcome/follow up.
RESULTS: Twelve patients treated by resection were identified. The location in the ten benign resected KCOTs was either the mandibular ramus or the posterior maxilla. All mandibular KCOTs exhibited perforation of the lingual plate and involvement of the pterygoid musculature. Seven of the ten cases were recurrent KCOTs and three had no prior treatment. Two had malignant changes in the KCOT and were also resected.
CONCLUSION: The primary reason for resection of KCOT was involvement of the pterygoid muscles. The presence of malignant change was a separate indication for resection.

Entities:  

Keywords:  KCOT; Keratocyst; OKC; Tumor

Year:  2015        PMID: 26225044      PMCID: PMC4511895          DOI: 10.1007/s12663-014-0732-7

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  25 in total

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Review 2.  Interventions for the treatment of keratocystic odontogenic tumours (KCOT, odontogenic keratocysts (OKC)).

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Authors:  Michele Giuliani; Giovanni Battista Grossi; Carlo Lajolo; Michele Bisceglia; Kathleen E Herb
Journal:  J Oral Maxillofac Surg       Date:  2006-02       Impact factor: 1.895

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Authors:  Teresa A Morgan; Christopher C Burton; Fang Qian
Journal:  J Oral Maxillofac Surg       Date:  2005-05       Impact factor: 1.895

8.  Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters.

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Authors:  Patricia González-Alva; Akio Tanaka; Yuka Oku; Dai Yoshizawa; Shigeru Itoh; Hideaki Sakashita; Fumio Ide; Yoshifumi Tajima; Kaoru Kusama
Journal:  J Oral Sci       Date:  2008-06       Impact factor: 1.556

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  4 in total

1.  Conservative surgical treatments for nonsyndromic odontogenic keratocysts: a systematic review and meta-analysis.

Authors:  Mayara Santos de Castro; Clenivaldo Alves Caixeta; Marina Lara de Carli; Noé Vital Ribeiro Júnior; Marta Miyazawa; Alessandro Antônio Costa Pereira; Felipe Fornias Sperandio; João Adolfo Costa Hanemann
Journal:  Clin Oral Investig       Date:  2017-12-20       Impact factor: 3.573

2.  Topical 5-fluorouracil application in management of odontogenic keratocysts.

Authors:  Parveen Akhter Lone; Nisar Ahmed Wani; Zubair Ahmed Janbaz; Mehnaz Bibi; Amit Kour
Journal:  J Oral Biol Craniofac Res       Date:  2020-07-22

3.  Long-term observation of a large keratocystic odontogenic tumour of the mandible treated by a single enucleation procedure: A case report and literature review.

Authors:  Tobias L Pittl; Marius Meier; Paul Hakl; Walter Sutter; Dritan Turhani
Journal:  Int J Surg Case Rep       Date:  2017-03-23

4.  A rare case of odontogenic keratocyst extending into the sphenoid bone from the maxilla.

Authors:  Mitsuo Goto; Sei Ueda; Satoru Miyabe; Satoshi Watanabe; Yoshihiko Sugita; Toru Nagao
Journal:  Int J Surg Case Rep       Date:  2020-05-21
  4 in total

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