Literature DB >> 26222626

Multiresolution Topological Simplification.

Kelin Xia1, Zhixiong Zhao1, Guo-Wei Wei1,2,3.   

Abstract

Persistent homology has been advocated as a new strategy for the topological simplification of complex data. However, it is computationally intractable for large data sets. In this work, we introduce multiresolution persistent homology for tackling large datasets. Our basic idea is to match the resolution with the scale of interest so as to create a topological microscopy for the underlying data. We adjust the resolution via a rigidity density-based filtration. The proposed multiresolution topological analysis is validated by the study of a complex RNA molecule.

Entities:  

Keywords:  big data; multiresolution topology; persistent homology; rigidity function

Mesh:

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Year:  2015        PMID: 26222626      PMCID: PMC4575524          DOI: 10.1089/cmb.2015.0104

Source DB:  PubMed          Journal:  J Comput Biol        ISSN: 1066-5277            Impact factor:   1.479


  6 in total

1.  Fast and anisotropic flexibility-rigidity index for protein flexibility and fluctuation analysis.

Authors:  Kristopher Opron; Kelin Xia; Guo-Wei Wei
Journal:  J Chem Phys       Date:  2014-06-21       Impact factor: 3.488

2.  Persistent topology for cryo-EM data analysis.

Authors:  Kelin Xia; Guo-Wei Wei
Journal:  Int J Numer Method Biomed Eng       Date:  2015-05-06       Impact factor: 2.747

3.  Multidimensional persistence in biomolecular data.

Authors:  Kelin Xia; Guo-Wei Wei
Journal:  J Comput Chem       Date:  2015-05-30       Impact factor: 3.376

4.  Persistent homology analysis of protein structure, flexibility, and folding.

Authors:  Kelin Xia; Guo-Wei Wei
Journal:  Int J Numer Method Biomed Eng       Date:  2014-06-24       Impact factor: 2.747

5.  Persistent homology for the quantitative prediction of fullerene stability.

Authors:  Kelin Xia; Xin Feng; Yiying Tong; Guo Wei Wei
Journal:  J Comput Chem       Date:  2014-12-19       Impact factor: 3.376

6.  Multiscale multiphysics and multidomain models--flexibility and rigidity.

Authors:  Kelin Xia; Kristopher Opron; Guo-Wei Wei
Journal:  J Chem Phys       Date:  2013-11-21       Impact factor: 3.488

  6 in total
  3 in total

1.  Evolutionary homology on coupled dynamical systems with applications to protein flexibility analysis.

Authors:  Zixuan Cang; Elizabeth Munch; Guo-Wei Wei
Journal:  J Appl Comput Topol       Date:  2020-07-29

2.  TopologyNet: Topology based deep convolutional and multi-task neural networks for biomolecular property predictions.

Authors:  Zixuan Cang; Guo-Wei Wei
Journal:  PLoS Comput Biol       Date:  2017-07-27       Impact factor: 4.475

3.  Gene Coexpression Network Comparison via Persistent Homology.

Authors:  Ali Nabi Duman; Harun Pirim
Journal:  Int J Genomics       Date:  2018-09-19       Impact factor: 2.326

  3 in total

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