Literature DB >> 26222064

The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.

Susan C Lipsett1, Nira R Pollock, John A Branda, Caroline D Gordon, Catherine R Gordon, Paul M Lantos, Lise E Nigrovic.   

Abstract

By using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high ELISA index values are strongly predictive of Lyme disease. In children with clinical presentations consistent with Lyme disease, ELISA index values ≥3.0 had a positive predictive value of 99.4% (95% confidence interval: 98.1-99.8%) for Lyme disease, making a supplemental Western immunoblot potentially unnecessary.

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Year:  2015        PMID： 26222064      PMCID： PMC4630803          DOI： 10.1097/INF.0000000000000858

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  13 in total

1.  High frequency of false positive IgM immunoblots for Borrelia burgdorferi in clinical practice.

Authors:  V Seriburi; N Ndukwe; Z Chang; M E Cox; G P Wormser
Journal:  Clin Microbiol Infect       Date:  2012-02-28       Impact factor: 8.067

2.  Prediction of Lyme meningitis in children from a Lyme disease-endemic region: a logistic-regression model using history, physical, and laboratory findings.

Authors:  Robert A Avery; Gary Frank; Joseph J Glutting; Stephen C Eppes
Journal:  Pediatrics       Date:  2006-01       Impact factor: 7.124

3.  Two-tiered antibody testing for Lyme disease with use of 2 enzyme immunoassays, a whole-cell sonicate enzyme immunoassay followed by a VlsE C6 peptide enzyme immunoassay.

Authors:  John A Branda; Katy Linskey; Yeowon A Kim; Allen C Steere; Mary Jane Ferraro
Journal:  Clin Infect Dis       Date:  2011-09       Impact factor: 9.079

4.  The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.

Authors:  Gary P Wormser; Raymond J Dattwyler; Eugene D Shapiro; John J Halperin; Allen C Steere; Mark S Klempner; Peter J Krause; Johan S Bakken; Franc Strle; Gerold Stanek; Linda Bockenstedt; Durland Fish; J Stephen Dumler; Robert B Nadelman
Journal:  Clin Infect Dis       Date:  2006-10-02       Impact factor: 9.079

5.  Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis.

Authors:  Keri A Cohn; Amy D Thompson; Samir S Shah; Elizabeth M Hines; Todd W Lyons; Elizabeth J Welsh; Lise E Nigrovic
Journal:  Pediatrics       Date:  2011-12-19       Impact factor: 7.124

6.  Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1995-08-11       Impact factor: 17.586

7.  Distinguishing Lyme from septic knee monoarthritis in Lyme disease-endemic areas.

Authors:  Julia K Deanehan; Amir A Kimia; Sharman P Tan Tanny; Matthew D Milewski; Paul G Talusan; Brian G Smith; Lise E Nigrovic
Journal:  Pediatrics       Date:  2013-02-18       Impact factor: 7.124

8.  Prospective validation of a clinical prediction model for Lyme meningitis in children.

Authors:  Aris C Garro; Maia Rutman; Kari Simonsen; Jenifer L Jaeger; Kimberle Chapin; Gregory Lockhart
Journal:  Pediatrics       Date:  2009-05       Impact factor: 7.124

9.  Empiric antibiotic treatment of erythema migrans-like skin lesions as a function of geography: a clinical and cost effectiveness modeling study.

Authors:  Paul M Lantos; R Jory Brinkerhoff; Gary P Wormser; Robert Clemen
Journal:  Vector Borne Zoonotic Dis       Date:  2013-10-09       Impact factor: 2.133

10.  Clinical predictors of Lyme disease among children with a peripheral facial palsy at an emergency department in a Lyme disease-endemic area.

Authors:  Lise E Nigrovic; Amy D Thompson; Andrew M Fine; Amir Kimia
Journal:  Pediatrics       Date:  2008-10-17       Impact factor: 7.124
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  3 in total

Review 1.  Diagnosis, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: A Review.

Authors:  Edgar Sanchez; Edouard Vannier; Gary P Wormser; Linden T Hu
Journal:  JAMA       Date:  2016-04-26       Impact factor: 56.272

Review 2.  Laboratory Diagnosis of Lyme Borreliosis.

Authors:  John A Branda; Allen C Steere
Journal:  Clin Microbiol Rev       Date:  2021-01-27       Impact factor: 26.132

3.  A Bayesian spatio-temporal model for forecasting the prevalence of antibodies to Borrelia burgdorferi, causative agent of Lyme disease, in domestic dogs within the contiguous United States.

Authors:  Stella C Watson; Yan Liu; Robert B Lund; Jenna R Gettings; Shila K Nordone; Christopher S McMahan; Michael J Yabsley
Journal:  PLoS One       Date:  2017-05-04       Impact factor: 3.240
  3 in total

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