| Literature DB >> 26218115 |
Daniela Kalafatovic1, Max Nobis, Nadeem Javid, Pim W J M Frederix, Kurt I Anderson, Brian R Saunders, Rein V Ulijn.
Abstract
Phenylacetyl-peptide amphiphiles were designed, which upon cleavage by a disease-associated enzyme reconfigure from micellar aggregates to fibres. Upon this morphological change, a doxorubicin payload could be retained in the fibres formed, which makes them valuable carriers for localised formation of nanofibre depots for slow release of hydrophobic anticancer drugs.Entities:
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Year: 2014 PMID: 26218115 DOI: 10.1039/c4bm00297k
Source DB: PubMed Journal: Biomater Sci ISSN: 2047-4830 Impact factor: 6.843