Literature DB >> 26217926

Prevalence and Characteristics of Discogenic Pain in Tertiary Practice: 223 Consecutive Cases Utilizing Lumbar Discography.

Paul Verrills1, Gillian Nowesenitz1, Adele Barnard1.   

Abstract

BACKGROUND: Between 26% and 42% of chronic low back pain is attributed to internal disc disruption of lumbar intervertebral discs. These prevalence estimates and data characterizing discogenic pain originate largely from research at elite practices, conducted 20 years ago. With few studies since, their concordance with rates in community practice has rarely been addressed.
OBJECTIVE: To assess the prevalence and key features of discogenic pain within community-based tertiary practice, and to evaluate the accuracy and clinical utility of discography.
DESIGN: This prospective, three-year study of 223 consecutive cases of chronic low back pain used image-guided lumbar discography to identify symptomatic and flanking asymptomatic discs. A subset of patients (n = 195) had previously undergone posterior column blocks to investigate spinal facet and/or sacroiliac joints as contributing pain sources.
RESULTS: A total of 644 discs were tested without infection or complication. Positive discograms were recorded in 74% of patients, with 22.9% negative and 3.1% assessed as indeterminate. Among patients receiving both discography and diagnostic blocks, 63% had proven discogenic pain, 18% had pain of mixed etiology and 14% remained undiagnosed. Taking into account all low back pain cases during this study (n = 756), discogenic pain prevalence was 21.8% (95% CI: 17-26%).
CONCLUSION: The prevalence of discogenic pain in this community practice is below the range, but within confidence intervals, previously reported. Prevalence is considerably elevated, however, among well-selected patients and discography enabled a firm diagnosis in most such cases. These findings are broadly in keeping with those reached in key publications and support the clinical utility of discography. Wiley Periodicals, Inc.

Entities:  

Keywords:  Disc Degeneration; Discogenic Pain; Discogram; Internal Disc Disruption; Lumbar Discography; Prevalence

Mesh:

Year:  2015        PMID: 26217926     DOI: 10.1111/pme.12809

Source DB:  PubMed          Journal:  Pain Med        ISSN: 1526-2375            Impact factor:   3.750


  9 in total

Review 1.  Treatment of Discogenic Low Back Pain: Current Treatment Strategies and Future Options-a Literature Review.

Authors:  Lei Zhao; Laxmaiah Manchikanti; Alan David Kaye; Alaa Abd-Elsayed
Journal:  Curr Pain Headache Rep       Date:  2019-11-09

2.  In Reply.

Authors:  Hans-Raimund Casser
Journal:  Dtsch Arztebl Int       Date:  2016-08-22       Impact factor: 5.594

3.  Clear Diagnosis and Therapy Are Possible.

Authors:  Thomas Bambach
Journal:  Dtsch Arztebl Int       Date:  2016-08-22       Impact factor: 5.594

Review 4.  Disorders of the spine. A major health and social problem.

Authors:  Filip Raciborski; Robert Gasik; Anna Kłak
Journal:  Reumatologia       Date:  2016-10-05

5.  The potential role and trend of HIF‑1α in intervertebral disc degeneration: Friend or foe? (Review).

Authors:  Yongjin Li; Shen Liu; Dayu Pan; Baoshan Xu; Xuewu Xing; Hengxing Zhou; Bin Zhang; Suzhe Zhou; Guangzhi Ning; Shiqing Feng
Journal:  Mol Med Rep       Date:  2021-02-04       Impact factor: 2.952

6.  Efficacy of the Gelstix nucleus augmentation device for the treatment of chronic discogenic low back pain: protocol for a randomised, sham-controlled, double-blind, multicentre trial.

Authors:  Eva Koetsier; Sander M J van Kuijk; Paolo Maino; Jasmina Dukanac; Luca Scascighini; Alessandro Cianfoni; Pietro Scarone; Dominique E Kuhlen; Markus W Hollman; Jan-Willem Kallewaard
Journal:  BMJ Open       Date:  2022-03-30       Impact factor: 2.692

7.  Clinical outcomes following intradiscal injections of higher-concentration platelet-rich plasma in patients with chronic lumbar discogenic pain.

Authors:  Cole Lutz; Jennifer Cheng; Meredith Prysak; Tyler Zukofsky; Rachel Rothman; Gregory Lutz
Journal:  Int Orthop       Date:  2022-03-28       Impact factor: 3.479

8.  Nucleoplasty for treating lumbar disk degenerative low back pain: an outcome prediction analysis.

Authors:  Po-Chou Liliang; Kang Lu; Cheng-Loong Liang; Ya-Wen Chen; Yu-Duan Tsai; Yuan-Kun Tu
Journal:  J Pain Res       Date:  2016-10-31       Impact factor: 3.133

9.  Ultrasound-Guided Lumbar Intradiscal Injection for Discogenic Pain: Technical Innovation and Presentation of Two Cases.

Authors:  Tsung-Ju Wu; Chen-Yu Hung; Chih-Wei Lee; Stanley Lam; Thomas B Clark; Ke-Vin Chang
Journal:  J Pain Res       Date:  2020-05-19       Impact factor: 3.133

  9 in total

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