Literature DB >> 26217074

Genomic medicine in gastroenterology: A new approach or a new specialty?

Sonia Roman1, Arturo Panduro1.   

Abstract

Throughout history, many medical milestones have been achieved to prevent and treat human diseases. Man's early conception of illness was naturally holistic or integrative. However, scientific knowledge was atomized into quantitative and qualitative research. In the field of medicine, the main trade-off was the creation of many medical specialties that commonly treat patients in advanced stages of disease. However, now that we are immersed in the post-genomic era, how should we reevaluate medicine? Genomic medicine has evoked a medical paradigm shift based on the plausibility to predict the genetic susceptibility to disease. Additionally, the development of chronic diseases should be viewed as a continuum of interactions between the individual's genetic make-up and environmental factors such as diet, physical activity, and emotions. Thus, personalized medicine is aimed at preventing or reversing clinical symptoms, and providing a better quality of life by integrating the genetic, environmental and cultural factors of diseases. Whether using genomic medicine in the field of gastroenterology is a new approach or a new medical specialty remains an open question. To address this issue, it will require the mutual work of educational and governmental authorities with public health professionals, with the goal of translating genomic medicine into better health policies.

Entities:  

Keywords:  Chronic diseases; Gastrointestinal diseases; Liver disease; Nutritional genomics; Obesity

Mesh:

Substances:

Year:  2015        PMID: 26217074      PMCID: PMC4507092          DOI: 10.3748/wjg.v21.i27.8227

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  67 in total

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2.  Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico.

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Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-11       Impact factor: 11.205

Review 3.  Genetic approaches to addiction: genes and alcohol.

Authors:  Francesca Ducci; David Goldman
Journal:  Addiction       Date:  2008-04-16       Impact factor: 6.526

4.  LDL cholesterol: should guidelines include targets?

Authors:  Subhash Banerjee; Dhiman Kahali; Avantika Banerjee; Emmanouil S Brilakis
Journal:  Expert Rev Cardiovasc Ther       Date:  2014-02-06

5.  Warriors versus worriers: the role of COMT gene variants.

Authors:  Dan J Stein; Timothy K Newman; Jonathan Savitz; Rajkumar Ramesar
Journal:  CNS Spectr       Date:  2006-10       Impact factor: 3.790

Review 6.  Hepatitis B virus infection in Latin America: a genomic medicine approach.

Authors:  Sonia Roman; Alexis Jose-Abrego; Nora Alma Fierro; Griselda Escobedo-Melendez; Claudia Ojeda-Granados; Erika Martinez-Lopez; Arturo Panduro
Journal:  World J Gastroenterol       Date:  2014-06-21       Impact factor: 5.742

Review 7.  Alcoholism and liver disease in Mexico: genetic and environmental factors.

Authors:  Sonia Roman; Eloy Alfonso Zepeda-Carrillo; Laura Eugenia Moreno-Luna; Arturo Panduro
Journal:  World J Gastroenterol       Date:  2013-11-28       Impact factor: 5.742

8.  The environment within: exploring the role of the gut microbiome in health and disease.

Authors:  Lindsey Konkel
Journal:  Environ Health Perspect       Date:  2013-09       Impact factor: 9.031

Review 9.  Molecular pathways in non-alcoholic fatty liver disease.

Authors:  Alba Berlanga; Esther Guiu-Jurado; José Antonio Porras; Teresa Auguet
Journal:  Clin Exp Gastroenterol       Date:  2014-07-05

Review 10.  A review and integrative analysis of ancient holistic character medicine systems.

Authors:  Søren Ventegodt; Suzette Thegler; Tove Andreasen; Flemming Struve; Susan Jacobsen; Margrethe Torp; Hans Aegedius; Lars Enevoldsen; Joav Merrick
Journal:  ScientificWorldJournal       Date:  2007-11-12
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  6 in total

1.  Early Detection of Liver Damage in Mexican Patients with Chronic Liver Disease.

Authors:  Rafael Torres-Valadez; Sonia Roman; Alexis Jose-Abrego; Maricruz Sepulveda-Villegas; Claudia Ojeda-Granados; Ingrid Rivera-Iñiguez; Arturo Panduro
Journal:  J Transl Int Med       Date:  2017-03-31

2.  CD36 genetic variation, fat intake and liver fibrosis in chronic hepatitis C virus infection.

Authors:  Omar Ramos-Lopez; Sonia Roman; Erika Martinez-Lopez; Nora A Fierro; Karina Gonzalez-Aldaco; Alexis Jose-Abrego; Arturo Panduro
Journal:  World J Hepatol       Date:  2016-09-08

3.  Need of righteous attitudes towards eradication of hepatitis C virus infection in Latin America.

Authors:  Arturo Panduro; Sonia Roman
Journal:  World J Gastroenterol       Date:  2016-06-14       Impact factor: 5.742

Review 4.  Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico.

Authors:  Omar Ramos-Lopez; Erika Martinez-Lopez; Sonia Roman; Nora A Fierro; Arturo Panduro
Journal:  World J Gastroenterol       Date:  2015-11-07       Impact factor: 5.742

Review 5.  Genes, emotions and gut microbiota: The next frontier for the gastroenterologist.

Authors:  Arturo Panduro; Ingrid Rivera-Iñiguez; Maricruz Sepulveda-Villegas; Sonia Roman
Journal:  World J Gastroenterol       Date:  2017-05-07       Impact factor: 5.742

6.  Association with Spontaneous Hepatitis C Viral Clearance and Genetic Differentiation of IL28B/IFNL4 Haplotypes in Populations from Mexico.

Authors:  Karina Gonzalez-Aldaco; João R Rebello Pinho; Sonia Roman; Ketti Gleyzer; Nora A Fierro; Leticia Oyakawa; Omar Ramos-Lopez; Rubia A Ferraz Santana; Roberta Sitnik; Arturo Panduro
Journal:  PLoS One       Date:  2016-01-07       Impact factor: 3.240

  6 in total

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