Literature DB >> 26216887

Sensorineural Hearing Loss: A Changing Paradigm for Its Evaluation.

Asitha D L Jayawardena1, A Eliot Shearer1, Richard J H Smith1,2,3.   

Abstract

OBJECTIVE: To determine how practicing clinicians evaluate patients with sensorineural hearing loss (SNHL) and to analyze the cost-effectiveness of current algorithms in the evaluation of these patients. STUDY DESIGN/
SETTING: An interactive online survey allowing respondents to order diagnostic testing in the evaluation of 4 simulated patients with SNHL across 2 testing encounters per patient. SUBJECTS AND METHODS: The survey was distributed to clinician members of the American Society of Pediatric Otolaryngology and the American Society of Human Genetics between May and August 2014. Statistical tests included chi-square and nonparametric testing with Mann-Whitney U test.
RESULTS: Otolaryngologists were significantly more likely than other clinicians to order repeat audiometric testing and significantly less likely to order genetic testing. Respondents who completed training more recently were significantly more likely to order magnetic resonance imaging and electrocardiogram. On average, respondents spent $4756 in the evaluation of a single patient, with otolaryngologists spending significantly more than other clinicians. Computed tomography of the temporal bone (40%), ophthalmology consultation (39%), and genetics consultation (37%) were ordered most frequently in the first encounter. Comprehensive genetic testing was ordered least frequently on the first encounter (20%) but was the most frequently ordered test on the second encounter (30%).
CONCLUSION: Recent guidelines advocate comprehensive genetic testing in the evaluation of patients with SNHL, as early genetic testing can prevent uninformative additional tests that otherwise increase health care expenditures. Results from this survey indicate that comprehensive genetic testing is now frequently but not uniformly included in evaluation of patients with SNHL. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2015.

Entities:  

Keywords:  DNA sequencing; deafness; genetic testing; hearing loss

Mesh:

Year:  2015        PMID: 26216887      PMCID: PMC4730883          DOI: 10.1177/0194599815596727

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  14 in total

1.  Etiologic and diagnostic evaluation: algorithm for severe to profound sensorineural hearing loss in Brazil.

Authors:  Priscila Zonzini Ramos; Vanessa Cristine Sousa de Moraes; Maria Carolina Costa Melo Svidnicki; Marcelo Naoki Soki; Arthur Menino Castilho; Edi Lúcia Sartorato
Journal:  Int J Audiol       Date:  2013-08-03       Impact factor: 2.117

2.  What is the optimal workup for a child with bilateral sensorineural hearing loss?

Authors:  Catherine K Hart; Daniel I Choo
Journal:  Laryngoscope       Date:  2013-04       Impact factor: 3.325

3.  Advancing genetic testing for deafness with genomic technology.

Authors:  A Eliot Shearer; E Ann Black-Ziegelbein; Michael S Hildebrand; Robert W Eppsteiner; Harini Ravi; Swati Joshi; Angelica C Guiffre; Christina M Sloan; Scott Happe; Susanna D Howard; Barbara Novak; Adam P Deluca; Kyle R Taylor; Todd E Scheetz; Terry A Braun; Thomas L Casavant; William J Kimberling; Emily M Leproust; Richard J H Smith
Journal:  J Med Genet       Date:  2013-06-26       Impact factor: 6.318

4.  Comprehensive diagnostic battery for evaluating sensorineural hearing loss in children.

Authors:  Jerry W Lin; Naweed Chowdhury; Avni Mody; Ross Tonini; Claudia Emery; Jody Haymond; John S Oghalai
Journal:  Otol Neurotol       Date:  2011-02       Impact factor: 2.311

5.  Carrier rates in the midwestern United States for GJB2 mutations causing inherited deafness.

Authors:  G E Green; D A Scott; J M McDonald; G G Woodworth; V C Sheffield; R J Smith
Journal:  JAMA       Date:  1999-06-16       Impact factor: 56.272

6.  A diagnostic paradigm for childhood idiopathic sensorineural hearing loss.

Authors:  Diego A Preciado; Lynne H Y Lim; Aliza P Cohen; Colm Madden; David Myer; Chris Ngo; John K Bradshaw; Louise Lawson; Daniel I Choo; John H Greinwald
Journal:  Otolaryngol Head Neck Surg       Date:  2004-12       Impact factor: 3.497

Review 7.  Sensorineural hearing loss in children.

Authors:  Richard J H Smith; James F Bale; Karl R White
Journal:  Lancet       Date:  2005 Mar 5-11       Impact factor: 79.321

Review 8.  Genetics: advances in genetic testing for deafness.

Authors:  A Eliot Shearer; Richard J H Smith
Journal:  Curr Opin Pediatr       Date:  2012-12       Impact factor: 2.856

9.  Etiologic and audiologic evaluations after universal neonatal hearing screening: analysis of 170 referred neonates.

Authors:  Frank Declau; An Boudewyns; Jenneke Van den Ende; Anouk Peeters; Paul van den Heyning
Journal:  Pediatrics       Date:  2008-06       Impact factor: 7.124

10.  Diagnostic application of targeted resequencing for familial nonsyndromic hearing loss.

Authors:  Byung Yoon Choi; Gibeom Park; Jungsoo Gim; Ah Reum Kim; Bong-Jik Kim; Hyo-Sang Kim; Joo Hyun Park; Taesung Park; Seung-Ha Oh; Kyu-Hee Han; Woong-Yang Park
Journal:  PLoS One       Date:  2013-08-22       Impact factor: 3.240

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  5 in total

1.  Medical Referral Patterns and Etiologies for Children With Mild-to-Severe Hearing Loss.

Authors:  Paul D Judge; Erik Jorgensen; Monica Lopez-Vazquez; Patricia Roush; Thomas A Page; Mary Pat Moeller; J Bruce Tomblin; Lenore Holte; Craig Buchman
Journal:  Ear Hear       Date:  2019 Jul/Aug       Impact factor: 3.570

Review 2.  Navigating genetic diagnostics in patients with hearing loss.

Authors:  Christina M Sloan-Heggen; Richard J H Smith
Journal:  Curr Opin Pediatr       Date:  2016-12       Impact factor: 2.856

3.  First glance at the molecular etiology of hearing loss in French-Canadian families from Saguenay-Lac-Saint-Jean's founder population.

Authors:  Tania Cruz Marino; Jessica Tardif; Josianne Leblanc; Janie Lavoie; Pascal Morin; Michel Harvey; Marie-Jacqueline Thomas; Annabelle Pratte; Nancy Braverman
Journal:  Hum Genet       Date:  2021-08-13       Impact factor: 4.132

Review 4.  The composition and capacity of the clinical genetics workforce in high-income countries: a scoping review.

Authors:  Nick Dragojlovic; Kennedy Borle; Nicola Kopac; Ursula Ellis; Patricia Birch; Shelin Adam; Jan M Friedman; Amy Nisselle; Alison M Elliott; Larry D Lynd
Journal:  Genet Med       Date:  2020-06-24       Impact factor: 8.822

Review 5.  Genetic and Non-genetic Workup for Pediatric Congenital Hearing Loss.

Authors:  Ryan Belcher; Frank Virgin; Jessica Duis; Christopher Wootten
Journal:  Front Pediatr       Date:  2021-03-22       Impact factor: 3.418

  5 in total

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