Visual impairment in a case of juvenile Paget's disease with pseudoxanthoma elasticum: an eleven year follow up.

An 11-year follow-up of a child presenting with Paget's disease of bone, and who subsequently developed pseudoxanthoma elasticum, is described. The influence of therapy on the ocular manifestations was disappointing. Calcitonin did not prevent the occurrence or progression of angioid streaks, and Argon laser photocoagulation of complicating subretinal neovascular membranes failed to prevent visual loss.