| Literature DB >> 26215391 |
Megan Crone1, Raymond Tellier2, Xing-Chang Wei3, Susan Kuhn4, Otto G Vanderkooi5, Jong Kim6, Jean K Mah1, Aleksandra Mineyko7.
Abstract
Poliomyelitis is a historically devastating neurological complication of poliovirus infection. Poliovirus vaccines have decreased the incidence of poliomyelitis to 209 global cases in 2014, with new cases of acute flaccid myelitis primarily associated with nonpolio enteroviruses. Recently, during outbreaks of enterovirus D68 throughout North America and Europe, cases of acute flaccid myelitis have been reported, suggesting another nonpolio enterovirus associated with acute flaccid myelitis. The authors describe 3 patients diagnosed with acute flaccid myelitis during a province-wide outbreak of enterovirus D68 with the virus detected in 2 of the patients. Given the significant morbidity associated with acute flaccid myelitis and potential for nonpolio enterovirus to cause outbreaks, prompt identification and notification of public health authorities are warranted.Entities:
Keywords: acute flaccid myelitis; acute flaccid paralysis; enterovirus D68; myelitis; poliovirus
Mesh:
Year: 2015 PMID: 26215391 DOI: 10.1177/0883073815596613
Source DB: PubMed Journal: J Child Neurol ISSN: 0883-0738 Impact factor: 1.987