Literature DB >> 26214572

On improving the credibility of candidate gene studies: A review of candidate gene studies published in Emotion.

Aysu Okbay1, Cornelius A Rietveld1.   

Abstract

The discovery of genetic variants associated with psychological traits deepens our knowledge about causes and consequences of individual differences. In psychology, the standard approach to identify these variants is the "candidate gene study." In a candidate gene study, a limited set of genetic variants is selected based on their hypothesized or known biological function, and these variants are tested for association with the psychological trait of interest. The successful replication of published candidate gene studies, however, is alarmingly scarce. In this article we describe the challenges to successfully identifying genetic associations, and review the candidate gene studies published in Emotion. We conclude that the implementation of 4 methodological guidelines developed by the Behavior Genetics Association for evaluating candidate gene studies will help to increase the credibility of candidate gene study findings. (c) 2015 APA, all rights reserved).

Mesh:

Year:  2015        PMID: 26214572     DOI: 10.1037/emo0000076

Source DB:  PubMed          Journal:  Emotion        ISSN: 1528-3542


  6 in total

1.  Childhood maltreatment, serotonin transporter gene, and risk for callous and unemotional traits: A prospective investigation.

Authors:  Cathy Spatz Widom; Dana Miller; Xuechen Li; Derek Gordon; Linda Brzustowicz
Journal:  Psychiatry Res       Date:  2020-07-02       Impact factor: 3.222

2.  The CogBIAS longitudinal study protocol: cognitive and genetic factors influencing psychological functioning in adolescence.

Authors:  Charlotte Booth; Annabel Songco; Sam Parsons; Lauren Heathcote; John Vincent; Robert Keers; Elaine Fox
Journal:  BMC Psychol       Date:  2017-12-29

3.  No association between genetic variants in MAOA, OXTR, and AVPR1a and cooperative strategies.

Authors:  María I Rivera-Hechem; Carlos Rodríguez-Sickert; Ricardo A Guzmán; Tadeo Ramírez-Parada; Felipe Benavides; Víctor Landaeta-Torres; Mauricio Aspé-Sánchez; Gabriela M Repetto
Journal:  PLoS One       Date:  2020-12-23       Impact factor: 3.240

4.  A Re-evaluation of Candidate Gene Studies for Well-Being in Light of Genome-Wide Evidence.

Authors:  Margot P van de Weijer; Dirk H M Pelt; Lianne P de Vries; Bart M L Baselmans; Meike Bartels
Journal:  J Happiness Stud       Date:  2022-05-17

Review 5.  Genetics of long-distance runners and road cyclists-A systematic review with meta-analysis.

Authors:  Magdalena Johanna Konopka; Jorn Carlos Maria Leonardus van den Bunder; Gerard Rietjens; Billy Sperlich; Maurice Petrus Zeegers
Journal:  Scand J Med Sci Sports       Date:  2022-07-26       Impact factor: 4.645

6.  Negative self-referential processing is associated with genetic variation in the serotonin transporter-linked polymorphic region (5-HTTLPR): Evidence from two independent studies.

Authors:  Justin Dainer-Best; Seth G Disner; John E McGeary; Bethany J Hamilton; Christopher G Beevers
Journal:  PLoS One       Date:  2018-06-13       Impact factor: 3.240

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.