Literature DB >> 2621359

Placental transfer of paracetamol.

M A Naga Rani, T Joseph, R Narayanan.   

Abstract

Paracetamol (1 g orally) was given to each of 10 healthy pregnant women undergoing normal vaginal delivery at the onset of second stage of labour. Following delivery, there was no significant difference in the serum concentration of paracetamol in the mother and the foetus (p less than 0.1), the mean value being 5.925 +/- 2.15 mg/ml and 7.875 +/- 2.22 mg/ml respectively. Paracetamol may be recommended as a safe analgesic-antipyretic during pregnancy and labour.

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Year:  1989        PMID: 2621359

Source DB:  PubMed          Journal:  J Indian Med Assoc        ISSN: 0019-5847


  10 in total

1.  Maternal paracetamol intake and fetal ductus arteriosus constriction/closure: comprehensive signal evaluation using the Austin Bradford Hill criteria.

Authors:  Manfred Hauben; Stephen Bai; Eric Hung; Kasia Lobello; Charles Tressler; Vincent P Zucal
Journal:  Eur J Clin Pharmacol       Date:  2021-01-07       Impact factor: 2.953

Review 2.  Placental transfer of drugs administered to the mother.

Authors:  G M Pacifici; R Nottoli
Journal:  Clin Pharmacokinet       Date:  1995-03       Impact factor: 6.447

3.  A COMPARATIVE STUDY OF INTRAMUSCULAR ACETAMINOPHEN VERSUS INTRAMUSCULAR PENTAZOCINE AS LABOUR ANALGESIA IN ZARIA, NORTHWESTERN NIGERIA.

Authors:  J C Ekweani; A G Adesiyun; E Ogboli-Nwasor; S Avidime
Journal:  J West Afr Coll Surg       Date:  2014 Jul-Sep

4.  Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model.

Authors:  Sander van den Driesche; Joni Macdonald; Richard A Anderson; Zoe C Johnston; Tarini Chetty; Lee B Smith; Chris Mckinnell; Afshan Dean; Natalie Z Homer; Anne Jorgensen; Maria-Elena Camacho-Moll; Richard M Sharpe; Rod T Mitchell
Journal:  Sci Transl Med       Date:  2015-05-20       Impact factor: 17.956

5.  Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental Systems.

Authors:  Pablo Hurtado-Gonzalez; Richard A Anderson; Joni Macdonald; Sander van den Driesche; Karen Kilcoyne; Anne Jørgensen; Chris McKinnell; Sheila Macpherson; Richard M Sharpe; Rod T Mitchell
Journal:  Environ Health Perspect       Date:  2018-04-16       Impact factor: 9.031

6.  In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.

Authors:  Moïra Rossitto; Margot Ollivier; Stéphanie Déjardin; Alain Pruvost; Christine Brun; Candice Marchive; Anvi Laetitia Nguyen; Aurélie Ghettas; Céline Keime; Bernard de Massy; Francis Poulat; Pascal Philibert; Brigitte Boizet-Bonhoure
Journal:  Commun Biol       Date:  2019-08-13

Review 7.  Using Experimental Models to Decipher the Effects of Acetaminophen and NSAIDs on Reproductive Development and Health.

Authors:  Brigitte Boizet-Bonhoure; Stéphanie Déjardin; Moïra Rossitto; Francis Poulat; Pascal Philibert
Journal:  Front Toxicol       Date:  2022-03-08

Review 8.  Maternal Paracetamol Intake During Pregnancy-Impacts on Offspring Reproductive Development.

Authors:  Rieko Tadokoro-Cuccaro; Benjamin G Fisher; Ajay Thankamony; Ken K Ong; Ieuan A Hughes
Journal:  Front Toxicol       Date:  2022-04-14

9.  Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences.

Authors:  Afshan Dean; Sander van den Driesche; Yili Wang; Chris McKinnell; Sheila Macpherson; Sharon L Eddie; Hazel Kinnell; Pablo Hurtado-Gonzalez; Tom J Chambers; Kerrie Stevenson; Elke Wolfinger; Lenka Hrabalkova; Ana Calarrao; Rosey Al Bayne; Casper P Hagen; Rod T Mitchell; Richard A Anderson; Richard M Sharpe
Journal:  Sci Rep       Date:  2016-01-27       Impact factor: 4.379

10.  Ibuprofen results in alterations of human fetal testis development.

Authors:  Millissia Ben Maamar; Laurianne Lesné; Kristin Hennig; Christèle Desdoits-Lethimonier; Karen R Kilcoyne; Isabelle Coiffec; Antoine D Rolland; Cécile Chevrier; David M Kristensen; Vincent Lavoué; Jean-Philippe Antignac; Bruno Le Bizec; Nathalie Dejucq-Rainsford; Rod T Mitchell; Séverine Mazaud-Guittot; Bernard Jégou
Journal:  Sci Rep       Date:  2017-03-10       Impact factor: 4.379

  10 in total

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