Ayman O Soubani1, Wei Chen2, Hyejeong Jang2. 1. Section of Pulmonary and Critical Care Medicine, Wayne State University School of Medicine, Detroit, MI, USA. Electronic address: asoubani@med.wayne.edu. 2. Department of Oncology, Karmanos Cancer Center, Wayne State University School of Medicine, Detroit, MI, USA.
Abstract
OBJECTIVE: To determine the 28 day mortality of patients with ARDS in relation to body mass index (BMI) and presence diabetes mellitus (DM). DESIGN: Retrospective cohort study of patients enrolled in the ARDS Network randomized controlled trials. RESULTS: 2914 patients were enrolled in these trials. 112 patients were underweight (BMI < 18.5), 948 patients were normal range (18.5 ≤ BMI < 25.0), 801 patients were overweight (25.0 ≤ BMI < 30.0), 687 patients were obese (30.0 ≤ BMI < 40.0), and 175 patients were severely obese (BMI ≥ 40.0). 469 patients had DM. There was no significant difference in the 28 day mortality in relation to BMI or presence of DM (underweight adjusted OR, 1.217; 95% CI, 0.749-1.979; overweight adjusted OR, 0.887; 95% CI, 0.696-1.131; obese adjusted OR, 0.812; 95% CI, 0.624-1.056; severely obese adjusted OR, 1.102; 95% CI, 0.716-1.695; and DM adjusted OR, 0.938; 95% CI, 0.728-1.208). CONCLUSIONS: The short term mortality in patients with ARDS is not affected by BMI or the presence of DM.
OBJECTIVE: To determine the 28 day mortality of patients with ARDS in relation to body mass index (BMI) and presence diabetes mellitus (DM). DESIGN: Retrospective cohort study of patients enrolled in the ARDS Network randomized controlled trials. RESULTS: 2914 patients were enrolled in these trials. 112 patients were underweight (BMI < 18.5), 948 patients were normal range (18.5 ≤ BMI < 25.0), 801 patients were overweight (25.0 ≤ BMI < 30.0), 687 patients were obese (30.0 ≤ BMI < 40.0), and 175 patients were severely obese (BMI ≥ 40.0). 469 patients had DM. There was no significant difference in the 28 day mortality in relation to BMI or presence of DM (underweight adjusted OR, 1.217; 95% CI, 0.749-1.979; overweight adjusted OR, 0.887; 95% CI, 0.696-1.131; obese adjusted OR, 0.812; 95% CI, 0.624-1.056; severely obese adjusted OR, 1.102; 95% CI, 0.716-1.695; and DM adjusted OR, 0.938; 95% CI, 0.728-1.208). CONCLUSIONS: The short term mortality in patients with ARDS is not affected by BMI or the presence of DM.