Literature DB >> 26211963

Potential extra-ribosomal functions of ribosomal proteins in Saccharomyces cerevisiae.

Hui Lu1, Yi-Fei Zhu1, Juan Xiong1, Rong Wang2, Zhengping Jia3.   

Abstract

Ribosomal proteins (RPs), are essential components of the ribosomes, the molecular machines that turn mRNA blueprints into proteins, as they serve to stabilize the structure of the rRNA, thus improving protein biosynthesis. In addition, growing evidence suggests that RPs can function in other cellular roles. In the present review, we summarize several potential extra-ribosomal functions of RPs in ribosomal biogenesis, transcription activity, translation process, DNA repair, replicative life span, adhesive growth, and morphological transformation in Saccharomyces cerevisiae. However, the future in-depth studies are needed to identify these novel secondary functions of RPs in S. cerevisiae.
Copyright © 2015 Elsevier GmbH. All rights reserved.

Entities:  

Keywords:  Extra-ribosomal function; Ribosomal protein; Saccharomyces cerevisiae

Mesh:

Substances:

Year:  2015        PMID: 26211963     DOI: 10.1016/j.micres.2015.05.004

Source DB:  PubMed          Journal:  Microbiol Res        ISSN: 0944-5013            Impact factor:   5.415


  17 in total

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