Ahmed Kayssi1, Ann DeBord Smith2, Graham Roche-Nagle3, Louis L Nguyen4. 1. Division of Vascular Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address: ahmed.kayssi@mail.utoronto.ca. 2. Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, Mass. 3. Division of Vascular Surgery, University of Toronto, Toronto, Ontario, Canada. 4. Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Abstract
OBJECTIVE: Endovascular repair (EVAR) of abdominal aortic aneurysms is a safe alternative to open aneurysm repair (OAR) in selected patients. The aim of this study was to compare the health-related quality-of-life (HR-QoL) outcomes of patients following EVAR and OAR. METHODS: A literature search of PubMed, EMBASE, and the Cochrane Library identified five randomized trials that reported on HR-QoL in EVAR and OAR for elective management of infrarenal abdominal aortic aneurysms. No consistent HR-QOL instrument was used among the studies. A meta-analysis was performed on the 36-Item Short Form (SF-36) and the EuroQol-5D (EQ-5D) HR-QoL results. RESULTS: SF-36 general health scores were higher for EVAR at 3, 6, and 12 months postoperatively. SF-36 physical functioning scores were higher for EVAR at 6 months but this advantage was lost at 12 months. In addition, SF-36 social functioning scores were higher for EVAR at 12 months. SF-36 component summary scores were not significantly different. EVAR was associated with a better EQ-5D score at 3, 6, and 12 months, but not at 24 months of follow-up. CONCLUSIONS: EVAR was associated with better HR-QoL in some domains up to 12 months postoperatively. There is insufficient data to demonstrate a HR-QoL advantage beyond 12 months. More studies are required to examine any long-term HR-QoL advantages for either intervention.
OBJECTIVE: Endovascular repair (EVAR) of abdominal aortic aneurysms is a safe alternative to open aneurysm repair (OAR) in selected patients. The aim of this study was to compare the health-related quality-of-life (HR-QoL) outcomes of patients following EVAR and OAR. METHODS: A literature search of PubMed, EMBASE, and the Cochrane Library identified five randomized trials that reported on HR-QoL in EVAR and OAR for elective management of infrarenal abdominal aortic aneurysms. No consistent HR-QOL instrument was used among the studies. A meta-analysis was performed on the 36-Item Short Form (SF-36) and the EuroQol-5D (EQ-5D) HR-QoL results. RESULTS: SF-36 general health scores were higher for EVAR at 3, 6, and 12 months postoperatively. SF-36 physical functioning scores were higher for EVAR at 6 months but this advantage was lost at 12 months. In addition, SF-36 social functioning scores were higher for EVAR at 12 months. SF-36 component summary scores were not significantly different. EVAR was associated with a better EQ-5D score at 3, 6, and 12 months, but not at 24 months of follow-up. CONCLUSIONS: EVAR was associated with better HR-QoL in some domains up to 12 months postoperatively. There is insufficient data to demonstrate a HR-QoL advantage beyond 12 months. More studies are required to examine any long-term HR-QoL advantages for either intervention.
Authors: Emanuel R Tenorio; Marina F Dias-Neto; Guilherme Baumgardt Barbosa Lima; Anthony L Estrera; Gustavo S Oderich Journal: Ann Cardiothorac Surg Date: 2021-11
Authors: Silvestra Barrena-Blázquez; Manuel Díez-Alonso; Luis Felipe Riera Del Moral; Salvador Sanchez-Coll; Melchor Alvarez-Mon; Miguel A Ortega; Fernando Ruiz-Grande Journal: Int J Environ Res Public Health Date: 2022-05-28 Impact factor: 4.614
Authors: Silvestra Barrena-Blázquez; Manuel Díez-Alonso; Luis Felipe Riera Del Moral; Salvador Sanchez Coll; Melchor Alvarez-Mon; Miguel A Ortega; Fernando Ruiz Grande Journal: J Clin Med Date: 2022-04-14 Impact factor: 4.964