Literature DB >> 2621114

Structural characterization of a metal-based perfusion tracer: copper(II) pyruvaldehyde bis(N4-methylthiosemicarbazone).

E John1, P E Fanwick, A T McKenzie, J G Stowell, M A Green.   

Abstract

Copper(II) pyruvaldehyde bis(N4-methylthiosemicarbazone), Cu(PTSM), has been obtained as a dark red crystalline solid from EtOH-DMSO solvent mixture and structurally characterized by x-ray crystallography. The molecule possesses the expected pseudo-square planar N2S2 metal coordination sphere; however, the copper center also interacts through its axial coordination site with the sulfur atom of an adjacent Cu(PTSM) molecule in the crystal lattice. The structure of this compound is compared with the structures of other metal complexes that have been proposed in the nuclear medicine literature as perfusion tracers.

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Year:  1989        PMID: 2621114     DOI: 10.1016/0883-2897(89)90163-3

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum B        ISSN: 0883-2897


  3 in total

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Journal:  Antimicrob Agents Chemother       Date:  2014-04-21       Impact factor: 5.191

Review 2.  Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging.

Authors:  Peter J Gawne; Francis Man; Philip J Blower; Rafael T M de Rosales
Journal:  Chem Rev       Date:  2022-05-12       Impact factor: 72.087

3.  Copper and zinc bis(thiosemicarbazonato) complexes with a fluorescent tag: synthesis, radiolabelling with copper-64, cell uptake and fluorescence studies.

Authors:  SinChun Lim; Katherine A Price; Siow-Feng Chong; Brett M Paterson; Aphrodite Caragounis; Kevin J Barnham; Peter J Crouch; Josephine M Peach; Jonathan R Dilworth; Anthony R White; Paul S Donnelly
Journal:  J Biol Inorg Chem       Date:  2009-09-22       Impact factor: 3.358

  3 in total

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