Literature DB >> 26210198

Inclusion of Adolescents and Young Adults in Cancer Clinical Trials.

Aaron R Weiss, Brandon Hayes-Lattin, Matthew A Kutny, Wendy Stock, Kristin Stegenga, David R Freyer.   

Abstract

OBJECTIVES: To discuss recent and current initiatives to increase enrollment of adolescents and young adult (AYA) cancer patients onto National Cancer Institute-funded clinical trials to improve outcomes. DATA SOURCES: Peer-reviewed publications, websites of professional organizations.
CONCLUSION: Despite many challenges facing AYAs, recent studies illustrate that AYA-focused cancer clinical trials can be successfully developed and conducted. Development of the National Cancer Institute National Clinical Trials Network and related AYA-focused initiatives create new opportunities to expand clinical trials that serve AYAs. IMPLICATIONS FOR NURSING PRACTICE: Nurses can influence AYA outcomes by leveraging their roles as educators and collaborators to increase participation in cancer clinical trials.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  AYA; Adolescent and young adult; cancer; clinical trials

Mesh:

Year:  2015        PMID: 26210198      PMCID: PMC5520996          DOI: 10.1016/j.soncn.2015.05.001

Source DB:  PubMed          Journal:  Semin Oncol Nurs        ISSN: 0749-2081            Impact factor:   2.315


  24 in total

1.  Clinical trial participation and time to treatment among adolescents and young adults with cancer: does age at diagnosis or insurance make a difference?

Authors:  Helen M Parsons; Linda C Harlan; Nita L Seibel; Jennifer L Stevens; Theresa H M Keegan
Journal:  J Clin Oncol       Date:  2011-09-19       Impact factor: 44.544

Review 2.  Adolescents and young adults with acute lymphoblastic leukemia have a better outcome when treated with pediatric-inspired regimens: systematic review and meta-analysis.

Authors:  Ron Ram; Ofir Wolach; Liat Vidal; Anat Gafter-Gvili; Ofer Shpilberg; Pia Raanani
Journal:  Am J Hematol       Date:  2012-03-03       Impact factor: 10.047

3.  Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial.

Authors:  Winette T A van der Graaf; Jean-Yves Blay; Sant P Chawla; Dong-Wan Kim; Binh Bui-Nguyen; Paolo G Casali; Patrick Schöffski; Massimo Aglietta; Arthur P Staddon; Yasuo Beppu; Axel Le Cesne; Hans Gelderblom; Ian R Judson; Nobuhito Araki; Monia Ouali; Sandrine Marreaud; Rachel Hodge; Mohammed R Dewji; Corneel Coens; George D Demetri; Christopher D Fletcher; Angelo Paolo Dei Tos; Peter Hohenberger
Journal:  Lancet       Date:  2012-05-16       Impact factor: 79.321

Review 4.  Acute lymphoblastic leukemia in young adults: which treatment?

Authors:  Jennifer L McNeer; Elizabeth A Raetz
Journal:  Curr Opin Oncol       Date:  2012-09       Impact factor: 3.645

Review 5.  Cancer in older adolescents and young adults: epidemiology, diagnosis, treatment, survival, and importance of clinical trials.

Authors:  W Archie Bleyer
Journal:  Med Pediatr Oncol       Date:  2002-01

Review 6.  Challenges in the recruitment of adolescents and young adults to cancer clinical trials.

Authors:  Megan E Burke; Karen Albritton; Neyssa Marina
Journal:  Cancer       Date:  2007-12-01       Impact factor: 6.860

7.  Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent/young adult and younger patients: a report from the Children's Oncology Group.

Authors:  Jason Canner; Todd A Alonzo; Janet Franklin; David R Freyer; Alan Gamis; Robert B Gerbing; Beverly J Lange; Soheil Meshinchi; William G Woods; John Perentesis; John Horan
Journal:  Cancer       Date:  2013-09-19       Impact factor: 6.860

8.  Adolescent and young adult (AYA) oncology: the first A.

Authors:  Archie Bleyer
Journal:  Pediatr Hematol Oncol       Date:  2007 Jul-Aug       Impact factor: 1.969

9.  Neuroblastoma in older children, adolescents and young adults: a report from the International Neuroblastoma Risk Group project.

Authors:  Yaël P Mossé; Rebecca J Deyell; Frank Berthold; Akira Nagakawara; Peter F Ambros; Tom Monclair; Susan L Cohn; Andrew D Pearson; Wendy B London; Katherine K Matthay
Journal:  Pediatr Blood Cancer       Date:  2013-09-13       Impact factor: 3.167

10.  Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children's oncology group.

Authors:  Smita Bhatia; Wendy Landier; Muyun Shangguan; Lindsey Hageman; Alexandra N Schaible; Andrea R Carter; Cara L Hanby; Wendy Leisenring; Yutaka Yasui; Nancy M Kornegay; Leo Mascarenhas; A Kim Ritchey; Jacqueline N Casillas; David S Dickens; Jane Meza; William L Carroll; Mary V Relling; F Lennie Wong
Journal:  J Clin Oncol       Date:  2012-05-07       Impact factor: 44.544

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  10 in total

Review 1.  Adolescent angst: enrollment on clinical trials.

Authors:  Theresa H M Keegan; Helen M Parsons
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2018-11-30

2.  Improving recruitment and retention of adolescents and young adults with cancer in randomized controlled clinical trials.

Authors:  Sharron L Docherty; Stacey Crane; Joan E Haase; Sheri L Robb
Journal:  Int J Adolesc Med Health       Date:  2019-04-11

3.  Survival of Adolescents and Young Adults with Prevalent Poor-Prognosis Metastatic Cancers: A Population-Based Study of Contemporary Patterns and Their Implications.

Authors:  Jessica K Sheth Bhutada; Amie E Hwang; Lihua Liu; Kai-Ya Tsai; Dennis Deapen; David R Freyer
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2022-04-01       Impact factor: 4.090

4.  Health Insurance Payer Type and Ethnicity Are Associated with Cancer Clinical Trial Enrollment Among Adolescents and Young Adults.

Authors:  Rebecca D Sullenger; Allison M Deal; Juneko E Grilley Olson; Melissa Matson; Catherine Swift; Lauren Lux; Andrew B Smitherman
Journal:  J Adolesc Young Adult Oncol       Date:  2021-05-19       Impact factor: 2.223

5.  Sink or Collaborate: How the Immersive Model Has Helped Address Typical Adolescent and Young Adult Barriers at a Single Institution and Kept the Adolescent and Young Adult Program Afloat.

Authors:  Damon R Reed; Benjamin Oshrine; Christie Pratt; Olivia Fridgen; Cathy Elstner; Leila Wilson; Hatem Soliman; Marie C Lee; Howard L McLeod; Bijal Shah; Kristine A Donovan; Smitha Pabbathi; Mary Turney; Odion Binitie; Christine Healy; Michael Nieder; Peter H Shaw; Andrew Galligan; G Douglas Letson; Marilyn Stern; Gwendolyn P Quinn; Simon Davies
Journal:  J Adolesc Young Adult Oncol       Date:  2017-08-04       Impact factor: 2.223

6.  Emerging Cancer Survival Trends, Disparities, and Priorities in Adolescents and Young Adults: A California Cancer Registry-Based Study.

Authors:  Diana J Moke; Kaiya Tsai; Ann S Hamilton; Amie Hwang; Lihua Liu; David R Freyer; Dennis Deapen
Journal:  JNCI Cancer Spectr       Date:  2019-06-12

Review 7.  Systematic review of barriers and facilitators to clinical trial enrollment among adolescents and young adults with cancer: Identifying opportunities for intervention.

Authors:  Elizabeth J Siembida; Holli A Loomans-Kropp; Neha Trivedi; Ann O'Mara; Lillian Sung; Irene Tami-Maury; David R Freyer; Michael Roth
Journal:  Cancer       Date:  2019-12-23       Impact factor: 6.921

8.  The HIV drug optimization agenda: promoting standards for earlier investigation and approvals of antiretroviral drugs for use in adolescents living with HIV.

Authors:  Pablo Rojo; Deborah Carpenter; François Venter; Anna Turkova; Martina Penazzato
Journal:  J Int AIDS Soc       Date:  2020-09       Impact factor: 5.396

9.  Cost-effectiveness of Anti-CD19 chimeric antigen receptor T-Cell therapy in pediatric relapsed/refractory B-cell acute lymphoblastic leukemia. A societal view.

Authors:  Frederick W Thielen; Annemieke van Dongen-Leunis; Alexander M M Arons; Judith R Ladestein; Peter M Hoogerbrugge; Carin A Uyl-de Groot
Journal:  Eur J Haematol       Date:  2020-05-04       Impact factor: 2.997

10.  Systems-Level Change to Alleviate Barriers to Cancer Clinical Trial Access for Adolescents and Young Adults in Australia.

Authors:  Justine A Ellis; Vajiranee S Malalasekera; Christie Allan; Peter F Choong; Jordan R Hansford; Ryan Hehir; Natasha Morello; Sally O'Callaghan; Lisa Orme; Nitya Phillipson; Mark A Rosenthal; Susan Sawyer; Robyn Strong; Leanne Super; Angela Watt; Chris Williams; Anne Woollett; Alexandra Robertson; Jeremy Lewin
Journal:  J Adolesc Young Adult Oncol       Date:  2021-07-22       Impact factor: 1.757

  10 in total

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