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Literature DB >> 2620816

[Genetic-epidemiologic analysis of uterine myoma: assessment of repeated risk].

M Kh Kurbanova, A G Koroleva, A S Sergeev.

Abstract

The results of myoma uteri family analysis are presented. Average estimates of family risks were: 26.6% for proband's sisters, 19.73% for proband's daughters (up to 44-years-old), 15.81% for proband's mothers. The estimate of heritability of the disease calculated according to the sibs data was 0.792 +/- 0.018, which points to the essential role of hereditary factors in the development of myoma uteri. The table of recurrence risk was calculated on the basis of the data obtained which may be used for forming risk groups in the course of mass physical examination.

Entities: Disease

Mesh：

Year: 1989 PMID： 2620816

Source DB: PubMed Journal: Genetika ISSN： 0016-6758

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Cited

11 in total

1. The impact of race as a risk factor for symptom severity and age at diagnosis of uterine leiomyomata among affected sisters.

Authors: Karen L Huyck; Carolien I M Panhuysen; Karen T Cuenco; Jingmei Zhang; Hilary Goldhammer; Emlyn S Jones; Priya Somasundaram; Allison M Lynch; Bernard L Harlow; Hang Lee; Elizabeth A Stewart; Cynthia C Morton
Journal: Am J Obstet Gynecol Date: 2008-02 Impact factor: 8.661

2. BET1L and TNRC6B associate with uterine fibroid risk among European Americans.

Authors: Todd L Edwards; Kara A Michels; Katherine E Hartmann; Digna R Velez Edwards
Journal: Hum Genet Date: 2013-04-19 Impact factor: 4.132

3. African ancestry and genetic risk for uterine leiomyomata.

Authors: Lauren A Wise; Edward A Ruiz-Narvaez; Julie R Palmer; Yvette C Cozier; Arti Tandon; Nick Patterson; Rose G Radin; Lynn Rosenberg; David Reich
Journal: Am J Epidemiol Date: 2012-11-15 Impact factor: 4.897

4. Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43.

Authors: N A Alam; S Bevan; M Churchman; E Barclay; K Barker; E E Jaeger; H M Nelson; E Healy; A C Pembroke; P S Friedmann; K Dalziel; E Calonje; J Anderson; P J August; M G Davies; R Felix; C S Munro; M Murdoch; J Rendall; S Kennedy; I M Leigh; D P Kelsell; I P Tomlinson; R S Houlston
Journal: Am J Hum Genet Date: 2001-03-14 Impact factor: 11.025

5. Association of germline mutations in the fumarate hydratase gene and uterine fibroids in women with hereditary leiomyomatosis and renal cell cancer.

Authors: Laveta Stewart; Gladys M Glenn; Pamela Stratton; Alisa M Goldstein; Maria J Merino; Margaret A Tucker; W Marston Linehan; Jorge R Toro
Journal: Arch Dermatol Date: 2008-12

[Genetic-epidemiologic analysis of uterine myoma: assessment of repeated risk].

1. The impact of race as a risk factor for symptom severity and age at diagnosis of uterine leiomyomata among affected sisters.

2. BET1L and TNRC6B associate with uterine fibroid risk among European Americans.

3. African ancestry and genetic risk for uterine leiomyomata.

4. Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43.

5. Association of germline mutations in the fumarate hydratase gene and uterine fibroids in women with hereditary leiomyomatosis and renal cell cancer.

Review 6. Epidemiology of Uterine Fibroids: From Menarche to Menopause.

7. Relationship between hysterectomy and admixture in African American women.

8. Uterine leiomyomata and decreased height: a common HMGA2 predisposition allele.

9. Variants in BET1L and TNRC6B associate with increasing fibroid volume and fibroid type among European Americans.

Review 10. Etiology and pathogenesis of uterine leiomyomas: a review.