Literature DB >> 26207944

A BODIPY-based 'turn-on' fluorescent probe for hypoxic cell imaging.

Sisi Wang1, Hui Liu, John Mack, Jiangwei Tian, Bin Zou, Hua Lu, Zhifang Li, Jianxiong Jiang, Zhen Shen.   

Abstract

A boron-dipyrromethene (BODIPY) dye containing a styryl substituent with a hydroxyl and nitro group, 1a, exhibits a 'turn-on' fluorescence response for hypoxic cells. The presence of the electron-withdrawing nitro group results in a highly efficient nonradiative decay of the S1 state, and hence a recovery of fluorescence intensity when nitro reduction occurs under hypoxic conditions.

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Year:  2015        PMID: 26207944     DOI: 10.1039/c5cc05139h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  8 in total

1.  Synthesis and spectroscopic properties of β,β'-dibenzo-3,5,8-triaryl-BODIPYs.

Authors:  Qianli Meng; Frank R Fronczek; M Graça H Vicente
Journal:  New J Chem       Date:  2016-02-08       Impact factor: 3.591

2.  Reversible Absorption and Emission Responses of Nile Blue and Azure A Derivatives in Extreme Acidic and Basic Conditions.

Authors:  Xiu-Li Wang; Ru Sun; Wei-Jin Zhu; Xin-Long Sha; Jian-Feng Ge
Journal:  J Fluoresc       Date:  2017-02-06       Impact factor: 2.217

3.  Synthesis and regioselective functionalization of perhalogenated BODIPYs.

Authors:  Ning Zhao; Sunting Xuan; Brandon Byrd; Frank R Fronczek; Kevin M Smith; M Graça H Vicente
Journal:  Org Biomol Chem       Date:  2016-06-02       Impact factor: 3.876

4.  A Genetically Encoded FRET Sensor for Hypoxia and Prolyl Hydroxylases.

Authors:  Suzan Youssef; Wei Ren; Hui-Wang Ai
Journal:  ACS Chem Biol       Date:  2016-07-14       Impact factor: 5.100

5.  Mechanochemical generation of singlet oxygen.

Authors:  Abdurrahman Turksoy; Deniz Yildiz; Simay Aydonat; Tutku Beduk; Merve Canyurt; Bilge Baytekin; Engin U Akkaya
Journal:  RSC Adv       Date:  2020-03-02       Impact factor: 4.036

6.  Real-time monitoring of newly acidified organelles during autophagy enabled by reaction-based BODIPY dyes.

Authors:  Hanzhuang Liu; Wenting Song; Delia Gröninger; Lei Zhang; Yinghong Lu; Kin Shing Chan; Zhikuan Zhou; Knut Rurack; Zhen Shen
Journal:  Commun Biol       Date:  2019-11-28

7.  A nitroreductase responsive and photoactivated fluorescent probe for dual-controlled tumor hypoxia imaging.

Authors:  Jialong Xu; Wenjing Zai; Qingsong Ye; Qingqing Zhang; Wenqian Yi; Jinhui Wu
Journal:  RSC Adv       Date:  2022-08-23       Impact factor: 4.036

Review 8.  Controllable Photodynamic Therapy Implemented by Regulating Singlet Oxygen Efficiency.

Authors:  Wenting Wu; Xiaodong Shao; Jianzhang Zhao; Mingbo Wu
Journal:  Adv Sci (Weinh)       Date:  2017-06-23       Impact factor: 16.806

  8 in total

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