| Literature DB >> 26207741 |
Fernanda de Oliveira Demitto, Renata Claro Ribeiro do Amaral, Flaviane Granero Maltempe, Vera Lúcia Dias Siqueira, Regiane Bertin de Lima Scodro, Mariana Aparecida Lopes, Katiany R Caleffi-Ferracioli, Pedro Henrique Canezin, Rosilene Fressatti Cardoso.
Abstract
Entities:
Year: 2015 PMID: 26207741 PMCID: PMC4514749 DOI: 10.1371/journal.pone.0133343
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 1Time-kill curve of the Mycobacterium tuberculosis H37Rv reference strain and multidrug-resistant clinical isolates 71A, 18, 19, 109, 3614, and 64A exposed to rifampicin (RIF), verapamil (VP), and RIF+VP combination for 7 days at 35–37°C.
Fig 2Fluorometry assay.
Accumulation of EtBr in the Mycobacterium tuberculosis HRv reference strain and multidrug-resistant clinical isolates 71A, 18, 19, 109, 3614, and 64A. The mycobacteria were loaded with 0.25 μg/ml EtBr in the presence of 0.5 × MIC of verapamil (VP), rifampicin (RIF), and RIF+VP combination for 7 days at 35–37°C.