Literature DB >> 26207447

Cyclopiazonic acid biosynthesis gene cluster gene cpaM is required for speradine A biosynthesis.

Masafumi Tokuoka1, Tomoki Kikuchi1, Yasutomo Shinohara2, Akifumi Koyama1, Shin-Ichiro Iio1, Takaaki Kubota3,4, Jun'ichi Kobayashi3, Yasuji Koyama2, Akira Totsuka5, Hitoshi Shindo1, Kazuo Sato1.   

Abstract

Speradine A is a derivative of cyclopiazonic acid (CPA) found in culture of an Aspergillus tamarii isolate. Heterologous expression of a predicted methyltransferase gene, cpaM, in the cpa biosynthesis gene cluster of A. tamarii resulted in the speradine A production in a 2-oxoCPA producing A. oryzae strain, indicating cpaM is involved in the speradine A biosynthesis.

Entities:  

Keywords:  Aspergillus oryzae; cyclopiazonic acid; secondary metabolism; speradine A

Mesh：

Substances：

Year:  2015        PMID： 26207447     DOI： 10.1080/09168451.2015.1065167

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  5 in total

1.  Taxonomy of Aspergillus section Flavi and their production of aflatoxins, ochratoxins and other mycotoxins.

Authors:  J C Frisvad; V Hubka; C N Ezekiel; S-B Hong; A Nováková; A J Chen; M Arzanlou; T O Larsen; F Sklenář; W Mahakarnchanakul; R A Samson; J Houbraken
Journal:  Stud Mycol       Date:  2018-07-31       Impact factor: 16.097

2.  Unravelling the Diversity of the Cyclopiazonic Acid Family of Mycotoxins in Aspergillus flavus by UHPLC Triple-TOF HRMS.

Authors:  Valdet Uka; Geromy G Moore; Natalia Arroyo-Manzanares; Dashnor Nebija; Sarah De Saeger; José Diana Di Mavungu
Journal:  Toxins (Basel)       Date:  2017-01-13       Impact factor: 4.546

3.  Aspergillus hancockii sp. nov., a biosynthetically talented fungus endemic to southeastern Australian soils.

Authors:  John I Pitt; Lene Lange; Alastair E Lacey; Daniel Vuong; David J Midgley; Paul Greenfield; Mark I Bradbury; Ernest Lacey; Peter K Busk; Bo Pilgaard; Yit-Heng Chooi; Andrew M Piggott
Journal:  PLoS One       Date:  2017-04-05       Impact factor: 3.240

4.  Biofilm Mode of Cultivation Leads to an Improvement of the Entomotoxic Patterns of Two Aspergillus Species.

Authors:  Frédéric Francis; Florent Druart; José Diana Di Mavungu; Marthe De Boevre; Sarah De Saeger; Frank Delvigne
Journal:  Microorganisms       Date:  2020-05-11

Review 5.  Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei.

Authors:  Jens C Frisvad; Lars L H Møller; Thomas O Larsen; Ravi Kumar; José Arnau
Journal:  Appl Microbiol Biotechnol       Date:  2018-10-06       Impact factor: 4.813
  5 in total

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