Literature DB >> 26206000

Alzheimer's disease and modern lifestyle: what is the role of stress?

Elena Marcello1, Fabrizio Gardoni1, Monica Di Luca1.   

Abstract

This Editorial highlights a study by Baglietto-Vargas et al. 2015 published in this issue of J. Neurochem. Stress is one of the environmental factors that can contribute to Alzheimer's disease pathogenesis. However, the role of modern-life stress has not been investigated yet. The authors reveal that modern-life stress reduces the number of dendritic spines in the hippocampus of Alzheimer's disease transgenic mice. The mechanism underlying such effect involves an increase in corticotropin-releasing hormone (CRH) release that stimulates the amyloid precursor protein (APP) processing and fosters the generation of Amyloid-β, which negatively affects dendritic spines.
© 2015 International Society for Neurochemistry.

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Year:  2015        PMID: 26206000     DOI: 10.1111/jnc.13210

Source DB:  PubMed          Journal:  J Neurochem        ISSN: 0022-3042            Impact factor:   5.372


  10 in total

1.  Gestational Stress Augments Postpartum β-Amyloid Pathology and Cognitive Decline in a Mouse Model of Alzheimer's Disease.

Authors:  Zahra Jafari; Jogender Mehla; Bryan E Kolb; Majid H Mohajerani
Journal:  Cereb Cortex       Date:  2019-08-14       Impact factor: 5.357

2.  Population Neuroscience: Dementia Epidemiology Serving Precision Medicine and Population Health.

Authors:  Mary Ganguli; Emiliano Albanese; Sudha Seshadri; David A Bennett; Constantine Lyketsos; Walter A Kukull; Ingmar Skoog; Hugh C Hendrie
Journal:  Alzheimer Dis Assoc Disord       Date:  2018 Jan-Mar       Impact factor: 2.703

3.  Life-Course Contribution of Prenatal Stress in Regulating the Neural Modulation Network Underlying the Prepulse Inhibition of the Acoustic Startle Reflex in Male Alzheimer's Disease Mice.

Authors:  Zahra Jafari; Bryan E Kolb; Majid H Mohajerani
Journal:  Cereb Cortex       Date:  2020-01-10       Impact factor: 5.357

4.  Intermittent hypoxia training protects cerebrovascular function in Alzheimer's disease.

Authors:  Eugenia B Manukhina; H Fred Downey; Xiangrong Shi; Robert T Mallet
Journal:  Exp Biol Med (Maywood)       Date:  2016-05-10

5.  Inhibition of ACE Retards Tau Hyperphosphorylation and Signs of Neuronal Degeneration in Aged Rats Subjected to Chronic Mild Stress.

Authors:  Said AbdAlla; Ahmed El Hakim; Ahmed Abdelbaset; Yasser Elfaramawy; Ursula Quitterer
Journal:  Biomed Res Int       Date:  2015-11-30       Impact factor: 3.411

Review 6.  Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration.

Authors:  Duraisamy Kempuraj; Ramasamy Thangavel; Govindhasamy P Selvakumar; Smita Zaheer; Mohammad E Ahmed; Sudhanshu P Raikwar; Haris Zahoor; Daniyal Saeed; Prashant A Natteru; Shankar Iyer; Asgar Zaheer
Journal:  Front Cell Neurosci       Date:  2017-07-24       Impact factor: 5.505

Review 7.  A preclinical perspective on the enhanced vulnerability to Alzheimer's disease after early-life stress.

Authors:  Lianne Hoeijmakers; Sylvie L Lesuis; Harm Krugers; Paul J Lucassen; Aniko Korosi
Journal:  Neurobiol Stress       Date:  2018-02-23

8.  Tauopathy in transgenic (SHR72) rats impairs function of central noradrenergic system and promotes neuroinflammation.

Authors:  Boris Mravec; Katarina Lejavova; Peter Vargovic; Katarina Ondicova; Lubica Horvathova; Petr Novak; Georg Manz; Peter Filipcik; Michal Novak; Richard Kvetnansky
Journal:  J Neuroinflammation       Date:  2016-01-20       Impact factor: 8.322

9.  Direct interaction of beta-amyloid with Na,K-ATPase as a putative regulator of the enzyme function.

Authors:  Irina Yu Petrushanko; Vladimir A Mitkevich; Anastasia A Anashkina; Alexei A Adzhubei; Ksenia M Burnysheva; Valentina A Lakunina; Yulia V Kamanina; Elena A Dergousova; Olga D Lopina; Omolara O Ogunshola; Anna Yu Bogdanova; Alexander A Makarov
Journal:  Sci Rep       Date:  2016-06-14       Impact factor: 4.379

10.  Association between Physical Activity and Cognitive Function among the Elderly in the Health and Social Centers in Kenitra, Rabat, and Sidi Kacem City (Morocco).

Authors:  Abdeljalil Talhaoui; Youssef Aboussaleh; Ahmed Ahami; Rachid Sbaibi; Naima Agoutim; Fatima Zohra Rouim; Khadija Karjouh
Journal:  Nutr Metab Insights       Date:  2021-07-01
  10 in total

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