Literature DB >> 26205803

Hydrazones as a privileged structural linker in antitubercular agents: a review.

Bijo Mathew1, Jerad Suresh, Mohamed J Ahsan, Githa E Mathew, Dhasthakeer Usman, Puthucode N S Subramanyan, Kallivalappil F Safna, Srinubabu Maddela.   

Abstract

Hydrazones are a versatile linker of connecting various classes of organic compounds with a unique structural feature of hydrogen bonding donor and the hydrogen bonding acceptor region. An extensive number of research has been carried out on hydrazone derivatives as a potent class of antitubercular agents. The present review focuses on the chemistry, antitubercular activity and structure activity relationship (SAR) of diverse classes of phenyl and heterocyclic based hydrazones.

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Year:  2015        PMID： 26205803     DOI： 10.2174/1871526515666150724104411

Source DB:  PubMed          Journal:  Infect Disord Drug Targets        ISSN： 1871-5265


  6 in total

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Journal:  Tetrahedron       Date:  2016-03-17       Impact factor: 2.457

2.  Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies.

Authors:  Ramkishore Matsa; Parameshwar Makam; Guneswar Sethi; Ahammed Ameen Thottasseri; Aswani Raj Kizhakkandiyil; Krishna Ramadas; Vignesh Mariappan; Agieshkumar Balakrishna Pillai; Tharanikkarasu Kannan
Journal:  RSC Adv       Date:  2022-06-22       Impact factor: 4.036

3.  Development of New Antimycobacterial Sulfonyl Hydrazones and 4-Methyl-1,2,3-thiadiazole-Based Hydrazone Derivatives.

Authors:  Violina T Angelova; Tania Pencheva; Nikolay Vassilev; Elena K-Yovkova; Rositsa Mihaylova; Boris Petrov; Violeta Valcheva
Journal:  Antibiotics (Basel)       Date:  2022-04-22

4.  Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.

Authors:  Bijo Mathew; Seung Cheol Baek; Della Grace Thomas Parambi; Jae Pil Lee; Monu Joy; P R Annie Rilda; Rugma V Randev; P Nithyamol; Vijitha Vijayan; Sini T Inasu; Githa Elizabeth Mathew; Krishnakumar K Lohidakshan; Girish Kumar Krishnan; Hoon Kim
Journal:  Medchemcomm       Date:  2018-09-25       Impact factor: 3.597

5.  Design, Synthesis, and Evaluation of a New Series of Thiazole-Based Anticancer Agents as Potent Akt Inhibitors.

Authors:  Mehlika Dilek Altıntop; Belgin Sever; Gülşen Akalın Çiftçi; Ahmet Özdemir
Journal:  Molecules       Date:  2018-05-31       Impact factor: 4.411

6.  Synthesis of hydrazides of heterocyclic amines and their antimicrobial and spasmolytic activity.

Authors:  Dmitriy A Berillo; Moldyr A Dyusebaeva
Journal:  Saudi Pharm J       Date:  2022-04-26       Impact factor: 4.562
  6 in total

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