| Literature DB >> 26203894 |
Anil Kumar Kusunuru1, Chaitanya K Jaladanki2, Madhu Babu Tatina1, Prasad V Bharatam2, Debaraj Mukherjee1.
Abstract
A palladium-catalyzed regio- and diastereoselective diarylation of glycals and pseudoglycals, which is a kind of Heck-Suzuki arylation, is described. A wide range of arylboronic acids reacted under these conditions smoothly. Selectivity was C1-C2(α,α) in the case of glycals but C2-C3(β,β) for pseudoglycals. Quantum chemical analysis has been carried out to establish the reaction mechanism, which may involve Pd(II)/Pd(O). TEMPO plays a key role in the formation of diaryl glycoside due to its radical nature.Entities:
Mesh：
Substances：
Year: 2015 PMID： 26203894 DOI： 10.1021/acs.orglett.5b01722
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005