Literature DB >> 26202314

Acute spinal cord compression: a rare complication of dual antiplatelet therapy.

Muhammad Zaid Iskandar1, Victor Chong1, Stuart Hutcheon1.   

Abstract

A 73-year-old woman presented with acute shortness of breath and exacerbation of chronic back pain. She was diagnosed with pulmonary oedema and a non-ST-elevation myocardial infarction following chest X-ray, ECG and high sensitivity troponin levels. She subsequently underwent coronary angioplasty with deployment of drug-eluting stents to her circumflex and left anterior descending arteries and was started on aspirin and clopidogrel for her dual antiplatelet therapy. Unfortunately, following the procedure, she gradually lost power and sensation in both lower limbs. MRI of her spine confirmed an extradural haematoma causing thoracic cord compression. She was managed conservatively following discussions with neurosurgeons and developed further complications secondary to her immobility. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26202314      PMCID: PMC4513563          DOI: 10.1136/bcr-2015-209952

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

1.  Relapsed spontaneous spinal epidural hematoma associated with aspirin and clopidogrel.

Authors:  Seong Hoon Lim; Bo Young Hong; Ye Rim Cho; Han Seung Kim; Jong In Lee; Hye Won Kim; Young Jin Ko
Journal:  Neurol Sci       Date:  2011-03-08       Impact factor: 3.307

2.  Management and neurological outcome of spontaneous spinal epidural hematoma.

Authors:  Tomasz Dziedzic; Przemysław Kunert; Piotr Krych; Andrzej Marchel
Journal:  J Clin Neurosci       Date:  2015-02-09       Impact factor: 1.961

3.  A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators.

Authors:  M B Leon; D S Baim; J J Popma; P C Gordon; D E Cutlip; K K Ho; A Giambartolomei; D J Diver; D M Lasorda; D O Williams; S J Pocock; R E Kuntz
Journal:  N Engl J Med       Date:  1998-12-03       Impact factor: 91.245

4.  [Acute cervical spinal epidural hematoma during antithrombotic therapy: dual warnings against antithrombotic therapy].

Authors:  Masae Toyonaga; Noriko Hagiwara; Fumi Irie; Kazunori Toyoda; Shigeru Fujimoto; Tsutomu Hitotsumatsu; Yasushi Okada
Journal:  Rinsho Shinkeigaku       Date:  2003-05

5.  Spontaneous spinal epidural hematoma: an urgent complication of adding clopidogrel to aspirin therapy.

Authors:  Hong-Joo Moon; Joo Han Kim; Jong-Hyun Kim; Taek-Hyun Kwon; Hung-Seob Chung; Youn-Kwan Park
Journal:  J Neurol Sci       Date:  2009-07-26       Impact factor: 3.181

  5 in total

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