Literature DB >> 26202281

Application of CPPs for Brain Delivery.

Artita Srimanee1, Jakob Regberg, Ülo Langel.   

Abstract

Cell-penetrating peptides provide a promising strategy for delivery of drugs across the blood-brain barrier. Here, we present an overview of CPP and peptide-mediated delivery to the central nervous system as well as a Transwell in vitro model to evaluate passage across an endothelial cell layer mimic of the blood-brain barrier.

Mesh:

Substances:

Year:  2015        PMID: 26202281     DOI: 10.1007/978-1-4939-2806-4_23

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  3 in total

1.  Cu, Zn-Superoxide Dismutase Increases the Therapeutic Potential of Adipose-derived Mesenchymal Stem Cells by Maintaining Antioxidant Enzyme Levels.

Authors:  Dae Young Yoo; Dae Won Kim; Jin Young Chung; Hyo Young Jung; Jong Whi Kim; Yeo Sung Yoon; In Koo Hwang; Jung Hoon Choi; Goang-Min Choi; Soo Young Choi; Seung Myung Moon
Journal:  Neurochem Res       Date:  2016-10-14       Impact factor: 3.996

2.  α-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease.

Authors:  Brian Spencer; Stephanie Williams; Edward Rockenstein; Elvira Valera; Wei Xin; Michael Mante; Jazmin Florio; Anthony Adame; Eliezer Masliah; Michael R Sierks
Journal:  Ann Clin Transl Neurol       Date:  2016-06-16       Impact factor: 4.511

3.  Role of autophagy in cell-penetrating peptide transfection model.

Authors:  Moataz Dowaidar; Maxime Gestin; Carmine Pasquale Cerrato; Mohammed Hakim Jafferali; Helerin Margus; Paula Ann Kivistik; Kariem Ezzat; Einar Hallberg; Margus Pooga; Mattias Hällbrink; Ülo Langel
Journal:  Sci Rep       Date:  2017-10-03       Impact factor: 4.379

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.